Amoxicillin for Treating Folliculitis: Efficacy and Concerns - Dermatology

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Amoxicillin for treating folliculitis?


I visited a dermatology clinic in Tainan around mid-June, where the doctor prescribed oral minocycline to treat my acne folliculitis.
After taking it for two weeks, the doctor felt that minocycline was not effective for my acne, so he switched me to oral amoxicillin.
After four weeks, my symptoms showed significant improvement, and I decided to stop the medication on my own, continuing only with topical clindamycin.
However, on August 8, I experienced a severe recurrence of folliculitis all over my body.
After the relapse, I consulted three different doctors at other clinics.
Some suggested that I had mixed folliculitis (fungal + bacterial), while others believed it was a fungal infection.
Eventually, I returned to the original clinic, where the doctor who initially treated me prescribed erythromycin, amoxicillin, and ibuprofen.
I have a few questions:
1.
Is it safe to use these three medications simultaneously?
2.
Can amoxicillin be used to treat folliculitis? (I remember it is not a typical treatment for acne folliculitis.)
3.
I have already been on amoxicillin for four weeks, with a two-week break in between.
Will continuing to take it pose a risk of antibiotic resistance? (The treatment over those four weeks was quite effective, and I can still accept the results when I look in the mirror.)

Xian Xian, 20~29 year old female. Ask Date: 2018/08/15

Dr. Wu Yuxin reply Dermatology


You should consult your attending physician about this issue, as they are most familiar with your condition and can help you choose the appropriate medication.

Reply Date: 2018/08/15

More Info


Amoxicillin is a commonly prescribed antibiotic that belongs to the penicillin group of drugs. It is often used to treat a variety of bacterial infections, including skin infections like folliculitis. However, there are important considerations regarding its efficacy and safety, especially in the context of your experience with folliculitis.


Efficacy of Amoxicillin for Folliculitis
Folliculitis is an infection of the hair follicles, which can be caused by bacteria, fungi, or even irritation from shaving or friction. While Amoxicillin is effective against certain bacterial infections, it is not typically the first-line treatment for folliculitis. The most common bacterial cause of folliculitis is Staphylococcus aureus, which can sometimes be resistant to penicillin-type antibiotics. Therefore, while Amoxicillin may help in some cases, it may not be the most effective choice for all patients, particularly if the infection is caused by a resistant strain or if there is a fungal component involved.

In your case, it seems that after initially using minocycline, which is often effective for acne-related folliculitis, you switched to Amoxicillin. You noted an improvement, which suggests that the bacterial component was responsive to the antibiotic. However, the recurrence of your symptoms indicates that there may be other factors at play, such as a mixed infection involving fungi, which Amoxicillin would not address.


Concerns About Concurrent Use of Medications
Regarding your question about the concurrent use of Amoxicillin, Clindamycin (the topical antibiotic), and Ibuprofen, it is generally safe to use these medications together. Amoxicillin and Clindamycin can complement each other, as they work through different mechanisms to combat bacterial infections. Ibuprofen, a non-steroidal anti-inflammatory drug (NSAID), can help reduce inflammation and pain associated with folliculitis. However, it is always best to consult with your healthcare provider before starting any new medications or combining treatments, as they can provide personalized advice based on your medical history.


Concerns About Antibiotic Resistance
You also expressed concern about the potential for antibiotic resistance after taking Amoxicillin for four weeks, especially since you had a two-week break in between. Antibiotic resistance can develop when antibiotics are used improperly or for extended periods without necessity. However, if Amoxicillin was effective in treating your folliculitis initially, it is less likely that you would develop resistance simply from a four-week course, especially if you followed the prescribed regimen.
That said, it is crucial to complete the full course of antibiotics as prescribed by your physician, even if you start to feel better. Stopping antibiotics prematurely can contribute to resistance and may allow the infection to return. If you are considering resuming Amoxicillin after a break, it is advisable to discuss this with your healthcare provider. They may want to reassess your condition to determine if a different treatment approach is necessary, especially if there is a suspicion of a fungal infection or if the folliculitis is recurrent.


Conclusion
In summary, while Amoxicillin can be used to treat folliculitis, its effectiveness may vary depending on the causative organism. The concurrent use of Amoxicillin, Clindamycin, and Ibuprofen is generally safe, but it is essential to consult with your healthcare provider for tailored advice. Lastly, concerns about antibiotic resistance should be taken seriously, and it is crucial to follow your doctor's recommendations regarding the duration and necessity of antibiotic therapy. If your symptoms persist or worsen, further evaluation may be necessary to explore other underlying causes or treatment options.

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