Stomach Issues: Symptoms, Diagnosis, and Treatment Options - Gastroenterology and Hepatology

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Gastrointestinal issues


Hello, doctor.
A few weeks ago, after eating a piece of fried chicken, I started to feel a loss of appetite.
My stomach doesn't hurt, but it feels a bit uncomfortable.
I had gastritis five years ago, and after taking medication from a clinic without improvement, I was referred to a hospital where the doctor recommended an endoscopy and biopsy.
The next day, the endoscopy revealed that I have an infection with Helicobacter pylori, gastroesophageal reflux disease, and the presence of ulcers.
The doctor prescribed antibiotics, and I am currently on the second day of treatment, but I still feel a bit of loss of appetite and nausea.
Additionally, my stool occasionally appears black, but it is very dry and in the form of small pellets.
I also experience pain when pressing on the area just below the right rib cage.

Could you please clarify if it takes a week to determine whether the biopsy results indicate malignancy in the ulcer? Or was the biopsy already completed on the day the doctor informed me about the Helicobacter pylori infection? If the ulcer is malignant, will I still be able to receive treatment? Thank you.

Songguo, 20~29 year old female. Ask Date: 2018/08/16

Dr. Chen Shidian reply Gastroenterology and Hepatology


Hello: The rapid examination of Helicobacter pylori through biopsy can be performed, while it may take about a week to check for the presence of gastric cancer through the biopsy.
Symptomatic treatment can be discussed further with your attending physician.
Changhua Hospital cares about your health.
Chen Shidian

Reply Date: 2018/08/16

More Info


Hello! It sounds like you are experiencing a complex set of gastrointestinal symptoms that can be quite distressing. Let's break down your situation and address your concerns regarding diagnosis, treatment options, and the implications of your symptoms.

From your description, it appears that you have a history of gastritis and have recently been diagnosed with a Helicobacter pylori (H. pylori) infection, gastroesophageal reflux disease (GERD), and a gastric ulcer. The treatment typically involves a combination of antibiotics to eradicate H. pylori and proton pump inhibitors (PPIs) to reduce stomach acid, allowing the ulcer to heal. It's important to follow your doctor's instructions regarding the medication regimen, as this can significantly impact your recovery.

Regarding your question about the biopsy results from the endoscopy, it is common for the pathologist to take a few days to a week to analyze the tissue samples. If a biopsy was performed during your endoscopy, the results would not be available immediately. The doctor may have been able to identify the presence of H. pylori during the procedure, but the biopsy results will provide more detailed information, including whether the ulcer is benign or malignant. If the biopsy indicates malignancy, treatment options would depend on the stage and type of cancer, and your healthcare team would discuss these options with you.

The presence of black, tarry stools (melena) can indicate bleeding in the upper gastrointestinal tract, which is a serious symptom that should not be ignored. This could be related to your ulcer, especially if it is bleeding. If you notice this symptom, it is crucial to seek medical attention promptly, as it may require urgent intervention.

Your symptoms of loss of appetite and nausea are also concerning. These can be side effects of the medications you are taking or could be related to the underlying conditions. It's essential to communicate these symptoms to your healthcare provider, as they may need to adjust your treatment plan or investigate further.

In terms of your question about whether psychological factors such as stress can affect the healing of ulcers and GERD, the answer is yes. Stress can exacerbate gastrointestinal symptoms and may hinder recovery. It is beneficial to incorporate stress management techniques into your routine, such as mindfulness, yoga, or counseling, to help alleviate some of the psychological burdens you may be experiencing.

Lastly, if your symptoms persist despite treatment, or if you develop new symptoms, it is essential to follow up with your healthcare provider. They may recommend additional tests, such as imaging studies or further endoscopic evaluations, to rule out other potential issues.

In summary, you are dealing with a multifaceted gastrointestinal issue that requires careful management. Ensure you are adhering to your prescribed treatment, monitor your symptoms closely, and maintain open communication with your healthcare team. They are your best resource for navigating these challenges and ensuring you receive appropriate care. Take care, and I wish you a smooth recovery!

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