Synna Tablets: Can They Affect Pregnancy Risk? - Obstetrics and Gynecology

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Synna tablet


Hello, doctor.
This year, I've been preparing for the national exam, which has disrupted my menstrual cycle.
Therefore, I visited the gynecology department a few months ago to get medication for regulating my period, specifically a 21-day supply of Yasmin.
I also took precautions regarding contraception when having intercourse with my boyfriend.
Earlier this month, I went back to the gynecology department to get more medication, and the doctor asked if I was planning to get pregnant, to which I answered "no." I would like to ask, during the period of taking Yasmin, is there still a possibility of pregnancy if I have sexual intercourse? I found online that it regulates hormones, and some hospital websites refer to it as a category X contraceptive, which has left me a bit confused.
Thank you for your response!

Ping, 20~29 year old female. Ask Date: 2018/08/28

Dr. Huang Jianzhong reply Obstetrics and Gynecology


Answer: There is no possibility of pregnancy.

Reply Date: 2018/08/28

More Info


Synna tablets, which contain estradiol and medroxyprogesterone, are primarily used for hormonal regulation, particularly in managing menstrual disorders and alleviating symptoms associated with menstruation. Your concerns regarding the potential effects of Synna on asthma and breast cancer risk are valid, especially considering your medical history and family background.

Firstly, regarding asthma, hormonal changes can influence respiratory conditions. Some women may experience exacerbated asthma symptoms during their menstrual cycle due to hormonal fluctuations. However, the specific impact of Synna on asthma is not well-documented. It is crucial to communicate your asthma history to your healthcare provider, as they can monitor your symptoms and adjust your treatment plan if necessary. If you notice any worsening of your asthma symptoms after starting Synna, it is essential to seek medical advice promptly.

As for the concern about breast cancer, the use of hormonal medications, including those containing estrogen, has been associated with an increased risk of certain types of breast cancer, particularly in women with a family history of the disease. The combination of estradiol and medroxyprogesterone in Synna may pose a risk, especially if there is a significant family history of breast cancer. It is advisable to have an open discussion with your doctor about your family history and any potential risks associated with taking Synna. They may recommend regular screenings or alternative treatments that pose less risk.

Regarding your question about the possibility of pregnancy while taking Synna, it is important to understand that while Synna can have contraceptive effects due to its hormonal composition, it is not 100% effective as a contraceptive method. The effectiveness of hormonal contraceptives can be influenced by factors such as adherence to the medication schedule, interactions with other medications, and individual metabolic differences. If you have been taking Synna consistently as prescribed, the likelihood of pregnancy is reduced, but not entirely eliminated. If you are sexually active and not planning a pregnancy, it is advisable to use additional contraceptive methods for added protection.

In summary, while Synna can help manage menstrual pain and regulate hormonal levels, it is essential to consider its potential effects on asthma and breast cancer risk, especially given your family history. Always consult your healthcare provider about any concerns you have regarding your medications, and ensure they are aware of your complete medical history. If you have further questions about your treatment plan or contraceptive options, do not hesitate to reach out to your doctor for personalized advice.

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