Do Dietary Supplements Interact with Bayer's Birth Control Pills? - Pharmacology

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Are there any interactions between the enteric-coated tablets and these vitamin components?


Hello, I would like to ask if the following ingredients in the dietary supplements I have been taking will affect the efficacy of the Bayer Yaz (combined oral contraceptive pill) or cause any interactions: glutathione, astaxanthin, Vitis vinifera (grape), ascorbic acid (vitamin C), citrus bioflavonoids, and vitamin D3.

nina, 20~29 year old female. Ask Date: 2018/09/15

Dr. Hou Fangmin reply Pharmacology


Hello Nina: The components of Yasmin you are taking are drospirenone 3mg and ethinylestradiol 0.03mg, and there are no interactions with the medications you are currently taking.
However, consuming it with foods such as coffee and grapefruit juice may lead to central nervous system stimulation, which can result in weight gain, headaches, and high blood pressure.
Therefore, it is advisable to be cautious and avoid coffee and grapefruit juice while taking Yasmin.
Wishing you safety and well-being.

Reply Date: 2018/09/15

More Info


When considering the interaction between dietary supplements and Bayer's birth control pills, it's essential to understand how certain substances can affect the efficacy of hormonal contraceptives. Bayer's birth control pills, like other oral contraceptives, work primarily by delivering hormones that prevent ovulation, thicken cervical mucus, and thin the uterine lining. Any substance that alters the metabolism of these hormones could potentially impact the effectiveness of the contraceptive.

1. Glutathione: This is a powerful antioxidant that plays a role in detoxification in the body. There is no substantial evidence to suggest that glutathione interacts with birth control pills. However, it is always wise to consult with a healthcare provider regarding its use, especially in high doses.

2. Astaxanthin: This is another antioxidant derived from microalgae and is known for its anti-inflammatory properties. Current research does not indicate that astaxanthin affects the metabolism of contraceptive hormones, so it is generally considered safe to use alongside birth control pills.

3. Vitis Vinifera (Grape Seed Extract): Grape seed extract is rich in antioxidants and has been studied for various health benefits. There is no significant evidence to suggest that it interacts with birth control pills. However, as with any supplement, it is advisable to monitor for any unusual side effects.

4. Ascorbic Acid (Vitamin C): Vitamin C is essential for immune function and skin health. While high doses of vitamin C can potentially affect the absorption of certain medications, there is no strong evidence to suggest that it significantly impacts the effectiveness of birth control pills.

5. Citrus Bioflavonoids: These compounds are found in citrus fruits and are known for their antioxidant properties. There is limited research on their interaction with birth control pills, but they are generally considered safe.

6. Vitamin D3: This vitamin is crucial for bone health and immune function. There is no evidence to suggest that vitamin D3 interacts with birth control pills, and it is often recommended for overall health.

In summary, the dietary supplements you mentioned—glutathione, astaxanthin, grape seed extract, vitamin C, citrus bioflavonoids, and vitamin D3—do not have well-documented interactions with Bayer's birth control pills. However, individual responses can vary, and the metabolism of medications can be influenced by various factors, including genetics, overall health, and the presence of other medications or supplements.

It is always best to consult with a healthcare provider or a pharmacist before starting any new supplements while on birth control pills. They can provide personalized advice based on your health history and any other medications you may be taking. Additionally, if you notice any unusual side effects or changes in your menstrual cycle after starting these supplements, it is important to discuss these with your healthcare provider.
Maintaining open communication with your healthcare provider about all supplements and medications you are taking will help ensure that you are using your birth control effectively and safely.

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