Helicobacter Pylori: Do You Need Further Testing? - Gastroenterology and Hepatology

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Helicobacter pylori


Hello Doctor: Recently, my blood test results from a health check showed a Helicobacter pylori level of 96.6 (positive) with <=10 (negative).
I don't have any specific discomfort in my gastrointestinal tract.
Should I go to the hospital for further examination? Is this level considered high? Thank you.

Aqi, 20~29 year old female. Ask Date: 2018/09/16

Dr. Chen Shidian reply Gastroenterology and Hepatology


Hello, due to the positive result for Helicobacter pylori and chronic gastritis, it is currently recommended to undergo an endoscopy or to consider out-of-pocket eradication therapy.
Changhua Hospital cares about your health.
Chen Shih-Dian

Reply Date: 2018/09/16

More Info


Hello! Thank you for your question regarding Helicobacter pylori (H. pylori) and the need for further testing based on your recent blood test results.

Based on your report, it appears that you have a positive result for H. pylori, with a value of 96.6, which is significantly above the threshold for a negative result (<=10). This indicates that you have been exposed to the bacteria, which is known to be associated with various gastrointestinal conditions, including chronic gastritis, peptic ulcers, and even gastric cancer in some cases.

1. Understanding H. pylori Testing: Blood tests for H. pylori typically measure antibodies against the bacteria. While a positive antibody test indicates that you have been exposed to H. pylori, it does not necessarily confirm an active infection. This is because antibodies can remain in the bloodstream even after the infection has been cleared. Therefore, while your result suggests a past or current infection, it does not provide definitive information about whether the bacteria are still present and active in your stomach.

2. Need for Further Testing: Given that you do not currently experience gastrointestinal discomfort, you might wonder if further testing is necessary. However, it is generally advisable to confirm the presence of active H. pylori infection, especially if you have a positive antibody test. The most common methods for confirming active infection include:
- Urea Breath Test (UBT): This non-invasive test measures the presence of urease, an enzyme produced by H. pylori, in your breath after consuming a specific carbon-labeled urea.

- Stool Antigen Test: This test detects H. pylori antigens in your stool, indicating an active infection.

- Endoscopy with Biopsy: In some cases, a doctor may recommend an endoscopy to visually inspect the stomach lining and take biopsies for histological examination.

3. Interpreting Your Results: Your reported value of 96.6 is indeed high and suggests a significant likelihood of H. pylori infection. While you may not currently have symptoms, the presence of H. pylori can lead to complications over time, such as the development of ulcers or chronic gastritis. Therefore, it is prudent to discuss with your healthcare provider the possibility of undergoing further testing to confirm the presence of the bacteria and determine the appropriate course of action.

4. Treatment Considerations: If further testing confirms an active H. pylori infection, treatment typically involves a combination of antibiotics and proton pump inhibitors (PPIs) to eradicate the bacteria and promote healing of the stomach lining. The standard treatment regimens, often referred to as "triple therapy" or "quadruple therapy," have high success rates in eradicating the infection.

5. Conclusion: In summary, while your blood test indicates exposure to H. pylori, further testing is recommended to confirm whether you have an active infection. This is important for determining the need for treatment to prevent potential complications. I encourage you to consult with your healthcare provider to discuss your results and the next steps in your care.

Thank you for your inquiry, and I hope this information helps you make an informed decision regarding your health!

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