and Managing Penile Ulcers: A Comprehensive Guide - Urology

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Balanitis with foreskin and glans ulceration?


Hello Doctor,
Since the end of July, I have noticed a red area on the inner side of my foreskin covering the glans, which developed into an ulcer after a few days.
When I retracted the foreskin, the corresponding area on the glans also appeared red.
I visited a clinic, and the doctor diagnosed me with balanoposthitis and prescribed LicoDerm ointment and a three-day course of antibiotics.
The condition of the foreskin injury gradually improved, but an ulcer appeared on the glans with some surrounding redness, and there were very small, irregular red bumps.
After two weeks without improvement, I consulted another doctor at the clinic, who suggested it might be herpes and prescribed some non-covered medications.
After a few more days without improvement, I went to the urology department of a regional hospital, where the doctor prescribed Fucicort ointment and Dicloxacillin.
A few days later, I noticed some discharge from the ulcer, so I stopped the medication and returned to the clinic.
The doctor told me that if it didn’t improve, I shouldn’t come back to see him.
Hearing this made me feel very discouraged, so the next day I went to a dermatology department at a medical center.
The doctor tested for HSV types 1 and 2, as well as syphilis, and prescribed a week’s worth of medications including Acyclovir ointment and Amoxicillin.
This time, the wound felt somewhat better, but I had a previous injury from masturbation that resulted in a linear small tear, which felt a bit painful when applying ointment.
Overall, I felt improvement, and blood tests showed HSV1 IgG positive, HSV2 IgG negative, and HSV Type I and II IgM index at 0.3 with a negative interpretation.

Over the next two to three weeks, the doctor continued to prescribe Acyclovir and a three-day course of Amoxicillin, and the wound gradually healed.
However, the previously red area on the foreskin now showed a slight color difference, leaning towards pink.
A few days ago, I noticed a small area on the glans that was more noticeably pink than before.
I started taking Amoxicillin again and applying Acyclovir, and within a day or two, the color improved again.
I stopped using Acyclovir, but it seems I need to finish the full three-day course of antibiotics.
I have about one day’s worth left, but I feel like I might also be experiencing an outbreak of oral herpes...

I have some questions: Is it really herpes? I haven’t had any clear or yellow blisters, nor have I had dense small rashes; only slightly irregular red swelling.
If I were to enlarge the red areas, they would resemble mosquito bites.
So far, I have three ulcer sites in sequence: on the inner foreskin, the glans, and another area on the glans, with the largest diameter not exceeding 0.5 cm.
HSV1 has tested positive, but I have previously had cold sores, and I have never engaged in any form of sexual activity.
It seems that each doctor I’ve seen doesn’t quite believe me...

However, there was one time when I was showering and accidentally spat phlegm onto the glans, but it was covered by the foreskin, only affecting the tip of the glans.
Since the wounds are all under the foreskin, is there a chance that HSV1 could have manifested on my foreskin or glans this way? I hope the doctor can take the time to clarify this for me.
I would greatly appreciate it!

Poorguy, 10~19 year old female. Ask Date: 2018/09/20

Dr. Du Shixi reply Urology


Hello: Herpes testing can only indicate that you have had an infection in the past; it does not confirm that this is a current herpes outbreak.
However, since you have developed ulcers, which are different from typical inflammation, there is still a possibility of herpes.
Since there has been no sexual activity, other sexually transmitted infections can be ruled out.
If it is herpes, it is important to pay special attention to lifestyle and immune function, as well as to care for the wounds (keeping them clean and dry).
Medications are only supportive; otherwise, recurrence is likely.
Some patients may experience several outbreaks in a year.
Wishing you good health.

Reply Date: 2018/09/20

More Info


Understanding and managing penile ulcers can be a complex issue, especially when multiple factors and potential diagnoses are involved. Based on your description, it seems you have experienced a series of symptoms that have led to various diagnoses, including balanitis (inflammation of the glans), herpes simplex virus (HSV) infection, and possibly other dermatological conditions.

Initial Symptoms and Diagnosis
You mentioned that your symptoms began with redness on the inner foreskin, which progressed to ulcers. This initial presentation could indeed be consistent with balanitis, which is often caused by irritation, infection, or an allergic reaction. The fact that you were prescribed topical treatments and antibiotics suggests that your healthcare providers were addressing a potential bacterial infection or inflammation.


Herpes Simplex Virus (HSV) Considerations
The subsequent diagnosis of herpes is significant. HSV can manifest as painful ulcers, typically accompanied by vesicular lesions (small blisters). However, it is important to note that not all herpes outbreaks present with the classic symptoms. Some individuals may experience atypical presentations, which can include small, irregularly shaped red lesions without the typical vesicles. Your positive HSV-1 IgG test indicates a past infection, which aligns with your history of oral herpes (cold sores).
The concern about whether HSV could be transmitted to the genital area through saliva is valid. While it is less common, it is possible for HSV-1 to cause genital herpes, particularly if there is direct contact with the virus during an outbreak. However, the absence of classic vesicular lesions makes it challenging to definitively diagnose your current condition as herpes without further clinical evaluation.


Ongoing Symptoms and Treatment
You have noted that the ulcers have shown some improvement with the use of Amoxicillin and topical treatments. It is crucial to complete the full course of antibiotics as prescribed, even if you start to feel better. Stopping antibiotics prematurely can lead to incomplete treatment of the infection and may contribute to antibiotic resistance.

The presence of new lesions or changes in color and texture of the skin can be concerning. It is essential to monitor these changes closely and report them to your healthcare provider. If the lesions do not improve or worsen, further evaluation may be necessary, including potential biopsy or additional laboratory tests to rule out other conditions.


Recommendations for Management
1. Follow-Up Care: Continue to follow up with your healthcare provider, especially if new symptoms arise or if the current treatment does not yield improvement. A dermatologist or urologist specializing in genital conditions may provide additional insights.

2. Avoid Irritants: Maintain good hygiene and avoid potential irritants, such as harsh soaps or lotions, that could exacerbate the condition. Gentle cleansing with mild soap and water is recommended.

3. Avoid Sexual Activity: Until you have a clear diagnosis and resolution of your symptoms, it is advisable to abstain from sexual activity to prevent potential transmission of infections and to avoid further irritation.

4. Educate Yourself: Understanding the nature of HSV and its management can help alleviate anxiety. Many individuals live with HSV and manage outbreaks effectively with antiviral medications.

5. Consider Counseling: If anxiety about your condition is affecting your quality of life, consider speaking with a mental health professional. They can provide strategies to cope with the stress associated with chronic health issues.

In conclusion, while your symptoms may suggest a herpes infection, the variability in presentation necessitates careful monitoring and possibly further investigation. It is essential to maintain open communication with your healthcare providers and adhere to treatment plans to achieve the best possible outcome.

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