When and How to Take Menstrual Regulation Medications - Obstetrics and Gynecology

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The appropriate timing and method for taking menstrual regulation medications are unclear?


Hello, Doctor.
My menstrual cycle and bleeding volume have been irregular for the past two years.
I visited a gynecologist and received medication to regulate my cycle, but I forgot where I put the medication and did not take it that month.
Now, it's the third month, and I found the medication, but I forgot how to take it.
The instructions on the medication bag are as follows: Provera Tab-10mg (take "twice daily," one tablet each time, for a total of 14 tablets, "for 7 days") and Estrogen Tab-0.625mg (Premarin) (take once daily, two tablets each time, for a total of 14 tablets, for 7 days).

My first question is: How should I take these two medications? Should I start taking them on the first day of my period, or can I take them at any time without waiting for my period? Additionally, I am confused because the doctor wrote a memo reminding me to take the Estrogen Tab-0.625mg (Premarin) (once daily, two tablets) first, and only after finishing the Estrogen should I take Provera.
However, the instructions on the medication bag for Provera differ, stating to take Provera Tab-10mg (once daily, one tablet, for a total of "14 days").

My second question is: Should I follow the instructions on the medication bag or the memo from the doctor? Please help clarify this for me.
Thank you.

Maddy, 40~49 year old female. Ask Date: 2018/09/22

Dr. Huang Yiwen reply Obstetrics and Gynecology


Hello, there are many methods to regulate menstruation, and each has its own unique techniques.
Doctors will prescribe different treatments based on each patient's individual circumstances; there are no strict rules on how to take menstrual regulation medications.
I recommend that you find a trusted obstetrician-gynecologist and discuss your situation with them.
They will help you find the most suitable prescription for you.

Reply Date: 2018/09/22

More Info


When it comes to understanding how to take menstrual regulation medications, it’s essential to follow the instructions provided by your healthcare provider, as they tailor the treatment to your specific needs. In your case, you have two medications: Provera (medroxyprogesterone acetate) and Premarin (conjugated estrogens). Let’s break down the instructions and clarify your questions.


1. Dosage Instructions:
- Provera (10 mg): According to the prescription, you should take this medication twice a day, one tablet at a time, for a total of 14 tablets over 7 days. This means you would take one tablet in the morning and one in the evening.

- Premarin (0.625 mg): This medication is prescribed to be taken once a day, with two tablets each time, for 14 days. This means you would take two tablets at the same time every day.


2. Timing of Medication:
- You asked whether to start taking these medications on the first day of your menstrual period or if you can start them at any time. Generally, hormonal medications like these can be started at any time, but it is often recommended to begin them at the start of your menstrual cycle for optimal results. However, since your doctor has provided specific instructions, it’s crucial to follow their guidance.

- In your case, since your doctor has indicated that you should take Premarin first, it seems they want you to start with the estrogen therapy before introducing the progesterone (Provera). This is often done to help regulate the menstrual cycle and manage symptoms effectively.


3. Conflicting Instructions:
- You mentioned a discrepancy between the instructions on the medication packaging and the memo from your doctor. It’s important to prioritize the instructions given by your healthcare provider, as they have a better understanding of your medical history and the specific reasons for prescribing these medications.

- If your doctor’s memo states to take Premarin first and then Provera, you should follow that advice. It’s not uncommon for healthcare providers to adjust standard dosing regimens based on individual patient needs.


4. General Recommendations:
- Consistency: Try to take your medications at the same time each day to maintain stable hormone levels in your body.

- Monitoring: Keep track of any changes in your menstrual cycle or any side effects you may experience while taking these medications. This information can be valuable for your healthcare provider in future consultations.

- Follow-Up: If you have any concerns about the medications or if you experience any adverse effects, do not hesitate to reach out to your healthcare provider for further guidance.


Conclusion:
In summary, you should take Premarin as instructed by your doctor before starting Provera, even if the packaging suggests a different regimen. Always prioritize your healthcare provider's instructions over the medication packaging, as they are tailored to your specific health needs. If you have any further questions or uncertainties, it’s best to consult with your doctor directly for clarification. Your health and well-being are paramount, and open communication with your healthcare provider is key to effective treatment.

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