Upper Abdominal Pain After Medication: Causes and Solutions

Upper abdominal pain after taking medication?

Hello Doctor: I experienced a sore throat on October 2nd and was diagnosed with pharyngitis at a clinic, after which I started taking medication.
I took the medication for three days, during which I felt a blockage in my stomach right after taking the medicine, accompanied by a warm sensation.
On the afternoon of October 5th, I visited another clinic where the doctor suggested that my stomach might be sensitive, causing discomfort from the medication.
This clinic prescribed a different medication, which did not cause the warm sensation like before.
However, I still experience ongoing stomach pain, especially when food passes through.
Could you please advise me on what might be causing my symptoms or what condition I may have? Should I see a doctor at a hospital?

Alina, 10~19 year old female. Ask Date: 2018/10/07

Dr. Chen Shidian reply Gastroenterology and Hepatology

Hello, it is possible that the pain relief and anti-inflammatory medication is irritating your stomach and esophagus.
It is recommended to discontinue use or to combine it with over-the-counter strong acid-reducing medications, or to undergo an endoscopy.
Changhua Hospital cares about your health.
Chen Shidian.

Reply Date: 2018/10/07

More Info

Upper abdominal pain after taking medication can be a concerning symptom, especially when it persists despite changing medications. In your case, it seems that the initial medication for your throat condition may have caused irritation or sensitivity in your stomach, leading to discomfort. Here are some potential causes and considerations regarding your symptoms:
1. Medication-Induced Gastritis: Some medications, particularly non-steroidal anti-inflammatory drugs (NSAIDs) and certain antibiotics, can irritate the gastric lining, leading to gastritis. Symptoms can include upper abdominal pain, nausea, and a burning sensation. If you were prescribed such medications, this could explain your discomfort.

2. Gastroesophageal Reflux Disease (GERD): If you are experiencing a burning sensation after taking medication, it could be related to acid reflux. GERD occurs when stomach acid flows back into the esophagus, causing irritation and pain. This condition can be exacerbated by certain medications, especially if taken on an empty stomach.

3. Peptic Ulcer Disease: If the pain is severe and persistent, it could indicate the presence of a peptic ulcer, which is a sore on the lining of the stomach or the first part of the small intestine. Ulcers can be aggravated by certain medications, particularly NSAIDs, and can cause significant discomfort.

4. Food Sensitivity or Intolerance: If you notice that the pain correlates with eating certain foods, it could be a sign of food intolerance or sensitivity. This is particularly relevant if you have a history of gastrointestinal issues.

5. Functional Dyspepsia: This is a common condition characterized by chronic or recurrent pain in the upper abdomen without an identifiable cause. It can be triggered by stress, dietary habits, or medication use.

Given your symptoms, it is advisable to seek further medical evaluation, especially since the pain persists. Here are some steps you can take:
- Consult a Gastroenterologist: A specialist can perform a thorough evaluation, which may include an endoscopy to visualize the stomach lining and check for ulcers or gastritis.

- Review Medications: Discuss all medications you have taken, including over-the-counter drugs, with your healthcare provider. They may consider adjusting your treatment plan.

- Dietary Modifications: Keeping a food diary to track what you eat and any associated symptoms can help identify potential triggers. Avoiding spicy, acidic, or irritating foods may also provide relief.

- Consider Antacids or Proton Pump Inhibitors: Over-the-counter medications that reduce stomach acid may help alleviate your symptoms. However, consult your doctor before starting any new medication.

- Stress Management: Since stress can exacerbate gastrointestinal symptoms, consider incorporating stress-reducing techniques such as mindfulness, yoga, or regular exercise into your routine.

In summary, while your symptoms may be related to medication sensitivity or gastrointestinal irritation, it is crucial to consult a healthcare provider for a comprehensive assessment. They can help determine the underlying cause of your upper abdominal pain and recommend appropriate treatment options. Early intervention can prevent complications and improve your quality of life.

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