Progesterone Use in Early Pregnancy After Miscarriages: Key Insights - Obstetrics and Gynecology

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Pregnancy Progesterone


Hello Doctor, I have had two miscarriages in the past, both at 7-8 weeks.
In both cases, there was a heartbeat initially, but it suddenly stopped.
I have undergone chromosomal and immune testing with my partner, and everything came back normal.
I am currently pregnant and have not experienced any bleeding.
I proactively asked my doctor to prescribe progesterone to help stabilize implantation.
The doctor advised me to take one pill in the morning and one in the evening.
Since the beginning of my pregnancy, I have been experiencing bloating.
I researched online and found that this could be due to the increase in progesterone during pregnancy.

1.
I would like to ask the doctor if I should continue taking progesterone in my situation.
Additionally, I am providing my test results from before my pregnancy for your reference: T4: 7.92, T3: 101.71, TSH: 1.12, LH: 4.90, FSH: 3.75, E2: 151.91, PRL: 8.38.

Niming, 30~39 year old female. Ask Date: 2018/10/31

Dr. Zhang Kunmin reply Obstetrics and Gynecology


Hello, based on your description, it is recommended to continue taking the medication and attending prenatal check-ups.
If you experience significant side effects, please discuss them with your obstetrician.
Thank you! Wishing you safety and health.
Dr.
Zhang

Reply Date: 2018/10/31

More Info


The use of progesterone in early pregnancy, especially for women with a history of miscarriages, is a topic of significant interest and importance. Progesterone is a hormone that plays a crucial role in maintaining pregnancy. It helps prepare the uterine lining for the implantation of a fertilized egg and supports the early stages of pregnancy by preventing uterine contractions that could lead to miscarriage.

In your case, having experienced two miscarriages at 7-8 weeks of gestation, it is understandable that you are seeking additional support through progesterone supplementation. Research indicates that progesterone can be beneficial for women with a history of recurrent pregnancy loss, particularly if the losses are associated with luteal phase defects or insufficient progesterone levels. The administration of progesterone can help stabilize the pregnancy by promoting a conducive environment for the embryo to implant and grow.

Given that you are currently pregnant and have not experienced any bleeding, the decision to continue progesterone supplementation should ideally be guided by your healthcare provider. Since your doctor has prescribed it, they likely believe that it is in your best interest to continue taking it, especially considering your previous pregnancy losses. The typical recommendation is to continue progesterone until at least the end of the first trimester, as this is when the placenta takes over hormone production to sustain the pregnancy.

Regarding your experience of bloating, it is not uncommon for women to experience gastrointestinal symptoms during early pregnancy, which can be attributed to hormonal changes, including increased progesterone levels. Progesterone can slow down gastrointestinal motility, leading to symptoms like bloating and discomfort. While these symptoms can be bothersome, they are generally not a cause for concern unless they are severe or accompanied by other alarming symptoms.

Your hormone levels, as indicated by the tests you provided, appear to be within normal ranges, which is reassuring. TSH, LH, FSH, and prolactin levels are important for assessing overall reproductive health, and your results suggest that your endocrine function is stable. However, it is essential to maintain regular follow-ups with your healthcare provider to monitor your pregnancy and adjust any medications as needed.

In summary, continuing progesterone supplementation in your situation seems prudent, especially given your history of miscarriages. It is crucial to maintain open communication with your healthcare provider about any symptoms you experience and to follow their guidance regarding medication use. They will consider your unique medical history and current pregnancy status when making recommendations. Remember to prioritize rest, manage stress, and maintain a healthy lifestyle to support your pregnancy. Wishing you a healthy and successful pregnancy journey!

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