Link Between Persistent Neck Lymph Node Swelling and Shoulder Pain? - Otolaryngology

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After three weeks of lymphadenopathy in the neck, a painful lump has appeared on the shoulder. Is there a connection?


Hello, doctor.
I am currently taking antibiotics because I have had lymphadenopathy in the left occipital region for three weeks without resolution.
After a CT scan, it was suggested that it might be Kikuchi disease, and I will have to wait until next week for an ultrasound to confirm the details.
However, this week I suddenly noticed a painful point on the left shoulder, specifically behind the protrusion of the shoulder bone, and it is the only point that is slightly raised.
I would like to know if this could be related to my lymphadenopathy, or if I should see a specialist in a particular field.
Thank you.

Wang, 30~39 year old female. Ask Date: 2018/11/18

Dr. Ji Zhaoyun reply Otolaryngology


Hello, based on your description, it is most likely that the enlargement of the cervical lymph nodes will be treated with some medications, and antibiotics may be used if necessary.
However, if the swelling in the neck continues to progress and leads to a deep neck infection, it is essential to take antibiotics and other medications.
As for Kikuchi disease, a biopsy is required for diagnosis through pathology reports.
If the condition is still progressing, it is advisable to consult an otolaryngologist and take medications as needed.
Wishing you peace and good health.
Sincerely, Chi Chao-Yun, Taichung Hospital, Ministry of Health and Welfare.

Reply Date: 2018/11/18

More Info


Persistent neck lymph node swelling, especially when associated with pain in the shoulder area, can indeed raise concerns about underlying conditions. In your case, the left posterior cervical lymph node swelling that has persisted for three weeks, along with the recent development of localized shoulder pain, warrants a thorough evaluation.

Firstly, it is important to understand the potential connections between lymph node swelling and shoulder pain. Lymph nodes are part of the immune system and can become enlarged due to infections, inflammation, or malignancies. In your case, the mention of "菊地式症" (likely referring to Kikuchi disease, a rare condition characterized by lymphadenopathy and fever) suggests that there may be an underlying inflammatory process affecting your lymphatic system. This condition can lead to localized pain and discomfort, which might explain the pain you are experiencing in your shoulder.

The shoulder pain you described, particularly the tender and slightly raised area behind the shoulder blade, could be related to referred pain from the cervical spine or the lymphatic system. The cervical spine can often be a source of referred pain to the shoulder due to nerve root irritation or compression, especially if there are underlying issues such as cervical spondylosis or disc herniation, as indicated in previous MRI reports. Additionally, the proximity of the lymph nodes to the shoulder area means that inflammation or irritation in the lymphatic system could potentially lead to localized pain in the shoulder.

Given that you are currently on antibiotics, it is crucial to monitor your symptoms closely. If the shoulder pain persists or worsens, or if you develop additional symptoms such as fever, night sweats, or significant weight loss, it would be prudent to seek further medical evaluation.
In terms of which specialty to consult, you may want to consider seeing an Ear, Nose, and Throat (ENT) specialist or a hematologist, as they are well-equipped to evaluate lymphatic issues. An ENT specialist can assess the lymph nodes and any potential connection to the cervical spine or shoulder pain. If Kikuchi disease is confirmed, follow-up with a hematologist may also be beneficial, as they can provide insights into management and any necessary further investigations.

In the meantime, it may be helpful to engage in gentle range-of-motion exercises for your neck and shoulder, as long as they do not exacerbate your pain. Applying warm compresses to the affected area may also provide some relief. However, avoid any strenuous activities that could aggravate your symptoms until you have a clearer understanding of your condition.

In summary, while there may be a connection between your persistent lymph node swelling and shoulder pain, a thorough evaluation by a medical professional is essential to determine the underlying cause and appropriate management. Keep track of your symptoms and do not hesitate to seek further medical advice if necessary.

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