Menstrual Issues: The Role of Estrogen and Ultrasound in Diagnosis - Obstetrics and Gynecology

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Menstrual issues


Doctor: If my period is delayed, can an ultrasound show if it's about to come? Is it possible that there is blood accumulation in the uterus? The doctor prescribed estrogen for me to take; does this help thicken the endometrium so that it can shed? Am I taking estrogen alone without progesterone? Will this balance my hormones and induce menstruation? I have researched a lot of information, and the doctor said that taking estrogen alone will raise the levels of estrogen in my body to a certain concentration.
Does this mean that it will stimulate the secretion of luteinizing hormone, and then without sexual intercourse, I will wait for it to drop and shed, resulting in my period? Will this also help expel any old blood from the uterus? Is this line of thinking correct? Doctor, please clarify how I can know if my uterus is recovering well.

Nü, 30~39 year old female. Ask Date: 2018/12/05

Dr. Huang Jianzhong reply Obstetrics and Gynecology


If my period hasn't come, can an ultrasound show if it's about to start? Answer: An ultrasound cannot reveal if there is blood accumulation in the uterus.
The doctor prescribed estrogen for me to take; does this help thicken the endometrium so that it can shed? Answer: Estrogen can thicken the endometrium and prevent it from shedding.
If I only take estrogen without progesterone, will that balance things out and lead to menstruation? Answer: Taking estrogen along with progesterone is necessary for balance.
I researched a lot of information, and the doctor advised me to take only estrogen.
If the estrogen levels in my body reach a certain concentration, will it then stimulate the secretion of luteinizing hormone, and if there is no sexual intercourse, will I then wait for it to decrease and shed, leading to menstruation? This would also help expel any retained blood in the uterus; is this thought correct? Answer: Yes, that is correct.
How can I know if my uterus is recovering well? Answer: Through ultrasound.

Reply Date: 2018/12/05

More Info


Understanding menstrual issues can be complex, particularly when it involves hormonal imbalances and the use of ultrasound for diagnosis. Let’s break down your questions and concerns regarding the role of estrogen, the use of ultrasound, and the implications for your menstrual cycle.

Firstly, when you mention that your period has not arrived, it’s important to understand that various factors can contribute to missed periods, including hormonal imbalances, stress, weight changes, and underlying medical conditions. An ultrasound can indeed be a useful tool in evaluating the reproductive organs, including the uterus and ovaries. It can help identify conditions such as polycystic ovary syndrome (PCOS), uterine fibroids, or even the presence of retained blood in the uterus (hematometra), which could be causing your menstrual irregularities.

Regarding the administration of estrogen, it is true that estrogen plays a crucial role in the menstrual cycle. Estrogen is responsible for the thickening of the endometrial lining in the uterus during the follicular phase of the cycle. If your doctor has prescribed estrogen, it is likely intended to stimulate the growth of the endometrial lining, which may have become thin or atrophied due to low estrogen levels. This thickening can eventually lead to the shedding of the lining, resulting in menstruation.

You asked whether taking estrogen alone, without progesterone (often referred to as progestin in hormone therapy), would be sufficient to balance your hormones and induce a menstrual period. In a typical menstrual cycle, estrogen levels rise in the first half, leading to the thickening of the endometrium, followed by a surge in luteinizing hormone (LH) that triggers ovulation. After ovulation, progesterone is produced by the corpus luteum, which stabilizes the endometrial lining. If pregnancy does not occur, progesterone levels drop, leading to menstruation.

If you are taking estrogen alone, it may lead to endometrial hyperplasia (thickening of the uterine lining) if not balanced with progesterone. This is particularly a concern for women who are not ovulating regularly, as the absence of progesterone can result in an unopposed estrogen effect. Therefore, while estrogen can help thicken the lining and potentially lead to a period, it is often recommended to use it in conjunction with progesterone to ensure a balanced hormonal environment and to prevent complications such as hyperplasia.

Your understanding that the body will eventually shed the lining if estrogen levels are adequate is partially correct, but it is essential to have the right hormonal balance. If you are not ovulating, simply increasing estrogen may not lead to a regular menstrual cycle without the counteracting effects of progesterone.

To assess whether your uterus is recovering well, your healthcare provider may recommend follow-up ultrasounds to monitor the thickness of the endometrial lining and check for any abnormalities. Additionally, tracking your menstrual cycle and any symptoms you experience can provide valuable information about your hormonal health.

In conclusion, while estrogen therapy can be beneficial in addressing menstrual irregularities, it is crucial to have a comprehensive approach that includes monitoring and possibly incorporating progesterone to ensure a balanced hormonal environment. Always consult with your healthcare provider for personalized advice and to discuss any concerns you may have regarding your treatment plan and menstrual health.

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