Ureteral Issues: Tumors, Stones, and Other Causes - Urology

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Ureteral issues


I am 32 years old and my health check report showed urine occult blood 1+ and RBC 2-5 HPF.
I have not done a urine re-examination and went directly to the urology department for an IUV examination and urine cytology.
Today, I returned to review the X-ray report of the IUV, which indicated a small segment of the right ureter that appears swollen.
However, the kidney ultrasound showed that the kidneys are normal, and the ureter does not seem to be obstructed.
Could this swollen segment be a ureteral tumor, a ureteral stone, or could there be other reasons? I am thinking that if it were a stone, it should be visible on the X-ray and would likely cause flank pain.
I asked the doctor, and he said the probability of it being a tumor is very low, but we still need to perform an endoscopic examination.
Additionally, the urine cytology analysis has not yet come back, but we have already decided to schedule a ureteroscopy for further investigation.
However, I am quite worried about the possibility of something serious inside, such as a cancerous tumor.
Are there any other potential causes? P.S.
I have been monitoring for any visible hematuria during urination, but it seems that has not occurred.

A-Kun, 30~39 year old female. Ask Date: 2018/12/06

Dr. Xu Wencang reply Urology


Follow-up outpatient visit to consult the physician in detail.

Reply Date: 2018/12/06

More Info


When it comes to ureteral issues such as tumors, stones, or other causes, it is essential to understand the various possibilities and the appropriate steps for diagnosis and management. Based on your situation, where a recent health check revealed hematuria (blood in urine) and subsequent imaging indicated a swollen segment of the right ureter, it is understandable to have concerns about the underlying cause.

Firstly, the presence of hematuria can arise from several conditions, including urinary tract infections (UTIs), kidney stones, benign tumors, or malignant tumors such as urothelial carcinoma. The fact that your kidney appears normal on ultrasound is reassuring, as it suggests that the kidney itself is not the source of the problem. However, the swollen segment of the ureter is a focal point of concern that warrants further investigation.

The differential diagnosis for a swollen ureter includes:
1. Ureteral Stones: While you mentioned that stones are typically visible on X-rays, not all stones are radiopaque. Some stones, particularly those made of uric acid, may not show up on standard imaging. Additionally, stones can cause swelling due to obstruction, leading to hydronephrosis (swelling of the kidney due to urine buildup). However, you noted that there is no blockage in the ureter, which makes this less likely.

2. Ureteral Tumors: Although your doctor indicated that the likelihood of a tumor is low, it remains a possibility, especially if there is swelling without a clear cause. Tumors can cause localized swelling and may not always present with symptoms like pain or visible blood in urine initially. The fact that you are undergoing a ureteroscopy (internal examination of the ureter) is a prudent step to rule out or confirm the presence of a tumor.

3. Inflammation or Infection: Conditions such as ureteritis or a urinary tract infection can cause localized swelling. Inflammation can occur due to various reasons, including infection or irritation from stones. If you have had any recent urinary symptoms, this could be a contributing factor.

4. Congenital Anomalies or Structural Issues: Sometimes, anatomical variations or previous surgeries can lead to changes in the ureter's appearance. These are less common but worth considering.

Given your situation, the decision to proceed with ureteroscopy is appropriate. This procedure will allow direct visualization of the ureter and any potential lesions, stones, or other abnormalities. Additionally, obtaining urine cytology results will provide further insight into the cellular composition of your urine, which can help identify any malignant cells if present.

While waiting for the procedure, it is essential to monitor your symptoms closely. Keep an eye out for any changes in urination patterns, such as increased frequency, urgency, or pain, as well as any new symptoms like fever or chills, which could indicate an infection.

In conclusion, while the possibility of a ureteral tumor exists, it is essential to consider all potential causes of the swelling. The upcoming ureteroscopy will be a critical step in determining the exact nature of the issue. It is natural to feel anxious about the possibility of a serious condition, but taking proactive steps in consultation with your healthcare provider will help ensure that you receive the appropriate care and treatment. Remember to discuss any concerns with your doctor, as they can provide you with the most accurate information based on your specific case.

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