the Use of Emergency Contraceptive Pills: FAQs and Concerns - Pharmacology

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28-tablet oral contraceptive pill


Your girlfriend's menstrual period started on the evening of November 30 and ended around December 5.
She purchased a 28-day oral contraceptive pill pack and took the first pill on the evening of December 10 at 10:30 PM, continuing to take the pills consistently (around 10:30 PM to midnight).
She finished the first 21 pills by December 30 and took the next 7 pills on December 31.

Question 1: Why hasn't her period started by January 1? Does she need to wait a few days for the "effect of the medication" to kick in? Is this considered normal?
Question 2: What should she do if her period doesn't come after these 7 days?
Question 3: Regardless of whether her period comes or not, should she continue taking the next pack after finishing these 7 pills?
Note: Sexual intercourse occurred between December 25 and 28 (with protection), and recently, your girlfriend has been experiencing some breast tenderness.

An, 10~19 year old female. Ask Date: 2019/01/01

Dr. Hong Kunyi reply Pharmacology


Hello, sir: After discussing with Dr.
Li from the Department of Obstetrics and Gynecology, I would like to provide the following advice.

Response to Question 1: The timing for taking the first pill of different brands of contraceptive pills varies, generally ranging from 1 to 5 days.
Your girlfriend's menstrual period started on the evening of November 30, and she took the first emergency contraceptive pill at 10:30 PM on December 10, which is already 10 days later.
Therefore, her period on January 1 is not expected to arrive, as the pill was taken late; please wait a few more days to see.
Response to Question 2: If her period does not come afterward, please take a pregnancy test or consult with an obstetrician-gynecologist.
Response to Question 3: Regardless of whether her period comes or not, it is recommended not to take the next pack immediately; it is better to wait about 5 days before starting the next pack.
Regarding your girlfriend's breast tenderness, it is advisable to consult with an obstetrician-gynecologist for more professional assistance.
Thank you for your message! Wishing you and your family peace and success.

Reply Date: 2019/01/01

More Info


Understanding the use of emergency contraceptive pills (ECPs) can be crucial for individuals who are concerned about unintended pregnancies. Based on your questions, I will address your concerns regarding the timing of your girlfriend's menstrual cycle after taking ECPs, what to do if her period does not arrive, and the continuation of her contraceptive regimen.


Question 1: Why hasn't my girlfriend's period arrived by January 1st? Is it normal to wait for the "effect" of the pills?
After taking emergency contraceptive pills, it is common for the menstrual cycle to be disrupted. ECPs, such as those containing levonorgestrel or ulipristal acetate, can delay ovulation and alter the menstrual cycle. The timing of the next period can vary significantly from person to person. It is not unusual for a period to be delayed for a few days or even a week after taking ECPs. The hormonal changes induced by the pills can lead to variations in the cycle, and it may take some time for the body to adjust.

In your girlfriend's case, since she took the ECPs on December 10th and has been consistent with her oral contraceptive regimen, it is possible that her period may still be on its way. It is important to remember that the effects of ECPs can vary, and while some women may experience their period on time, others may see a delay.


Question 2: What should we do if her period does not arrive after seven days?
If your girlfriend's period does not arrive within a week after the expected date, it is advisable for her to take a pregnancy test. ECPs are not 100% effective, and while the chances of becoming pregnant are reduced, they are not eliminated entirely. A home pregnancy test can provide clarity and help determine if she is pregnant. If the test is negative and her period still does not arrive, it may be wise for her to consult a healthcare provider for further evaluation. They can assess her situation and provide guidance on the next steps.


Question 3: Should she continue taking the next pack of pills regardless of whether her period arrives?
If your girlfriend is on a regular oral contraceptive regimen and has been taking her pills consistently, she should continue taking the next pack as scheduled, regardless of whether her period has arrived. This is important to maintain contraceptive efficacy and to ensure that she remains protected against unintended pregnancy. If her period is delayed, it is still safe to continue taking the pills, as long as she has not received a positive pregnancy test.


Additional Considerations
It is also worth noting that some women may experience side effects from ECPs, such as breast tenderness, nausea, or changes in mood. The breast tenderness your girlfriend is experiencing could be related to hormonal fluctuations caused by the ECPs or her regular contraceptive pills. If these symptoms persist or worsen, she should consult with a healthcare provider.

In summary, it is not uncommon for menstrual cycles to be disrupted after taking emergency contraceptive pills. If her period does not arrive within a week, taking a pregnancy test is a prudent step. Continuing her regular contraceptive regimen is important for ongoing protection. If there are any concerns or unusual symptoms, seeking medical advice is always recommended.

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