Pregnancy Testing: Accuracy, Timing, and Concerns - Obstetrics and Gynecology

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Pregnancy test questions?


I'm sorry, doctor, I would like to ask: My girlfriend's last menstrual period started on December 4.
Her cycle in the last four periods has been between 31 to 35 days, while in the previous six months, most of her cycles were between 35 to 44 days.
We had sexual intercourse on December 22 and January 1, both times using condoms and performing a water test, but as of now, January 12, her period has not arrived.
We suspect that it might be due to stress from final exams; she finally finished her exams on January 11, but we are still worried about the possibility of pregnancy.
On January 11, she used a pregnancy test from the brand Mentholatum, and the result was negative.
How accurate is this brand of pregnancy test? If she wants to test again, how many days should she wait? If it were an ectopic pregnancy, would the hCG levels be more difficult to detect, and how many days would it take? Based on your professional assessment, what is the likelihood of pregnancy, and when might her period be expected to arrive? Thank you, doctor.

Gh, 10~19 year old female. Ask Date: 2019/01/12

Dr. Huang Jianzhong reply Obstetrics and Gynecology


Your girlfriend's last menstrual period started on December 4.
Her cycle has ranged from 31 to 35 days in the last four cycles, while for the previous six months, most cycles were between 35 to 44 days.
You both had sexual intercourse on December 22 and January 1, using condoms and conducting a water test.
However, as of January 12, her period has not arrived.
You suspect that the stress from final exams may be a factor, and since she completed her exams on January 11, you are still concerned about the possibility of pregnancy.
On January 11, she used a pregnancy test from the Mentholatum brand, which returned a negative result.

Regarding the accuracy of this brand of pregnancy test, it is generally considered reliable, but if you want to test again, it is advisable to wait at least 7 days for more accurate results.
If there is a possibility of an ectopic pregnancy, the hCG levels may be more difficult to detect, and it typically takes a few days for levels to rise enough to be measured accurately.

An ectopic pregnancy is not necessarily more difficult to detect with a pregnancy test.
Based on a physician's professional assessment, if there is a high likelihood of pregnancy, it is recommended to perform an ultrasound to evaluate the situation further.

Reply Date: 2019/01/12

More Info


When it comes to understanding pregnancy testing, accuracy, timing, and concerns are crucial aspects that need to be addressed. Based on the details you've provided, your girlfriend's menstrual cycle has shown some variability, which can complicate the timing of pregnancy tests.
Firstly, the accuracy of home pregnancy tests, such as the one you mentioned (the Man Shu Lei Dun brand), is generally quite high when used correctly. Most home pregnancy tests claim to be over 99% accurate when used on the day of the expected period. However, since your girlfriend's cycle has been irregular, it may be beneficial to wait a few days after the expected period to retest. Given that her last menstrual period was on December 4, and considering her cycle length, she may not have been due for her period yet, depending on her cycle's variability.
If she tested on January 11 and received a negative result, it is advisable to wait a few days and test again, ideally around January 15 or 16. This allows for sufficient time for the hormone hCG (human chorionic gonadotropin) to build up in the urine if she is indeed pregnant.
Regarding ectopic pregnancy, it is important to note that while home pregnancy tests can detect hCG, they may not always indicate the location of the pregnancy. Ectopic pregnancies can sometimes result in lower hCG levels or abnormal increases, making them harder to detect with standard urine tests. If there is a suspicion of an ectopic pregnancy, especially if your girlfriend experiences symptoms like abdominal pain or unusual bleeding, it is critical to seek medical attention promptly.
In terms of the likelihood of pregnancy, given that you used condoms during intercourse, the chances of pregnancy are reduced, but not entirely eliminated, especially if there was any failure in the condom's integrity. Stress can also impact menstrual cycles, potentially delaying the onset of her period.
As for when her period might arrive, it can vary significantly based on her stress levels, hormonal balance, and overall health. If her period does not arrive within a week of the expected date, it would be advisable for her to consult a healthcare provider for further evaluation.
In summary, I recommend the following steps:
1. Retest for pregnancy a few days after the initial test, ideally around January 15 or 16.

2. Monitor for any symptoms of ectopic pregnancy, such as severe abdominal pain or unusual bleeding, and seek medical attention if these occur.

3. If her period does not arrive within a week of the expected date, consider scheduling an appointment with a healthcare provider for further evaluation and possibly a blood test, which can provide more accurate results regarding pregnancy status.

Understanding these factors can help alleviate some of the concerns you both may have. It's always best to consult with a healthcare professional for personalized advice and support.

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