Paget's Disease: Symptoms and Concerns in Young Adults - Breast and Thyroid

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I am 19 years old and have been experiencing some itching on the left nipple and areola for about a year.
The itching is not very severe, but sometimes I feel a sharp pain that is not tenderness; it is a sudden sharp sensation that lasts for about one to two minutes.
Additionally, I have a retracted (flat) nipple.
I have researched a lot online and found that unilateral symptoms may indicate Paget's disease.
I have seen two doctors, both of whom diagnosed it as eczema.
I have also had an ultrasound, and aside from the retraction, there were no other issues.
I would like to ask the doctor if this could be Paget's disease.
My friends and family, as well as the two doctors, have told me that it is not this condition, but I cannot help but worry.

Yiooo, 10~19 year old female. Ask Date: 2019/02/13

Dr. Yuan Tianmin reply Breast and Thyroid


Most cases of Behçet's disease are associated with poor ulcer healing, and itching is not one of its primary symptoms.
Your condition seems more like a skin-related issue.

Reply Date: 2019/02/13

More Info


Paget's disease of the breast, also known as Paget's disease of the nipple, is a rare condition that primarily affects the skin of the nipple and the area surrounding it (the areola). It is often associated with underlying breast cancer, particularly ductal carcinoma in situ (DCIS) or invasive breast cancer. Given your symptoms of itching, occasional sharp pain, and nipple retraction, it is understandable that you are concerned about the possibility of Paget's disease.


Symptoms of Paget's Disease
The symptoms of Paget's disease can vary, but they typically include:
1. Itching or Burning Sensation: This can be localized to the nipple and areola.

2. Redness and Scaling: The skin may appear red, scaly, or crusty.

3. Nipple Discharge: There may be a discharge from the nipple, which can be clear, yellow, or bloody.

4. Nipple Retraction: The nipple may appear flat or inverted.

5. Pain or Tenderness: Some individuals report discomfort or pain in the affected area.


Diagnosis
To diagnose Paget's disease, healthcare providers typically perform a thorough clinical examination and may recommend imaging studies such as a mammogram or ultrasound. A biopsy of the affected skin is often necessary to confirm the diagnosis and rule out or confirm the presence of cancerous cells.


Concerns in Young Adults
While Paget's disease is more commonly diagnosed in older women, it can occur in younger individuals as well. It is important to note that not all symptoms of nipple irritation or changes indicate Paget's disease. Conditions such as eczema, dermatitis, or other benign skin conditions can also cause similar symptoms.
Given that you have already consulted with two doctors who have suggested that your symptoms are likely due to eczema, it may be beneficial to seek a third opinion, particularly from a dermatologist or a breast specialist. They can provide a more comprehensive evaluation and, if necessary, perform a biopsy to rule out Paget's disease or any other serious conditions.


Treatment and Management
If your symptoms are indeed due to eczema or another benign condition, treatment may include:
- Topical Steroids: These can help reduce inflammation and itching.

- Moisturizers: Keeping the skin hydrated can alleviate dryness and irritation.

- Avoiding Irritants: Identifying and avoiding any potential irritants or allergens that may be causing your symptoms.

If Paget's disease is diagnosed, treatment will depend on the underlying cause, which may involve surgical intervention, radiation therapy, or other oncological treatments if cancer is present.


Conclusion
While your symptoms may be concerning, it is essential to approach the situation with a clear understanding of the possibilities. Paget's disease is a rare condition, and many other benign conditions can cause similar symptoms. Continuing to seek medical advice and possibly obtaining a biopsy will provide clarity and peace of mind. Remember, early detection and treatment are crucial in managing any potential issues effectively. If you have further concerns, do not hesitate to reach out to your healthcare provider for additional support and guidance.

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