Feasibility of Microblading for Patients with Favism

Q: Feasibility of Microblading for Patients with Favism

Dear Ms. <br>Wu：<br>1. <br>Glucose-6-phosphate dehydrogenase deficiency (G-6-PD deficiency) is an X-linked recessive genetic disorder, predominantly affecting males, and is more common among Hakka people in Taiwan. <br>The enzyme glucose-6-phosphate dehydrogenase (G-6-PD) located

Feasibility of Microblading for Individuals with Favism (G6PD Deficiency)

Hello, can patients with favism undergo the current popular eyebrow misting or feathering beauty treatments? Will plant-based pigments and post-procedure soothing ointments be used during the eyebrow misting or feathering process? Thank you for your response, doctor.

Ms. Wu, 20~29 year old female. Ask Date: 2019/02/19

Dr. Xiao Yongxun reply Family Medicine

Dear Ms.
Wu:
1.
Glucose-6-phosphate dehydrogenase deficiency (G-6-PD deficiency) is an X-linked recessive genetic disorder, predominantly affecting males, and is more common among Hakka people in Taiwan.
The enzyme glucose-6-phosphate dehydrogenase (G-6-PD) located in the red blood cell membrane protects red blood cells from oxidative damage and is also involved in glucose metabolism within these cells.
Patients with G-6-PD deficiency are unable to maintain adequate levels of reduced glutathione through the glucose metabolic pathway, making their cell membranes more susceptible to damage and leading to hemolysis.
Therefore, when patients are exposed to sulfonamides, camphor, antimalarial drugs, aspirin, and other analgesics, they are at risk of developing hemolytic anemia.
Additionally, some individuals may experience this condition after consuming fava beans, a phenomenon known as favism.
2.
Clinically, acute hemolytic crises may occur within hours of exposure to oxidants, characterized by a rapid decrease in hematocrit, an increase in plasma hemoglobin, and unconjugated bilirubin levels.
In severe cases, hemoglobinuria and even circulatory failure may develop.
Screening high-risk populations (such as Hakka individuals) and minimizing exposure to oxidant medications can help prevent hemolysis.
3.
Regarding the plant-based pigments and post-procedure soothing ointments used during the eyebrow tattooing process, it may be necessary to consult a medical aesthetics expert to determine their ingredients.
It is important to ascertain whether they contain sulfonamides, camphor, antimalarial drugs, aspirin, analgesics, or oxidants, as their presence could increase the risk of triggering favism.

Reply Date: 2019/02/19

More Info

When considering microblading or any cosmetic procedure for patients with favism (a condition characterized by a deficiency in the enzyme glucose-6-phosphate dehydrogenase, or G6PD), it is essential to evaluate the potential risks and benefits carefully. Favism can lead to hemolytic anemia when individuals consume fava beans or are exposed to certain medications and chemicals, which raises concerns about the safety of various cosmetic treatments.

Microblading involves the use of a handheld tool to create hair-like strokes in the skin, typically using a pigment that is implanted into the epidermis. The process may involve the application of topical anesthetics, pigments, and soothing ointments post-procedure. Here are some considerations for patients with favism:
1. Allergic Reactions and Sensitivities: Patients with favism may have heightened sensitivities to certain substances, including pigments and topical anesthetics used during microblading. It is crucial to conduct a patch test before the procedure to check for any allergic reactions. Ingredients in the pigments or soothing creams should be reviewed to ensure they do not contain any harmful substances for individuals with G6PD deficiency.

2. Infection Risk: Individuals with favism may have a compromised ability to respond to infections due to their condition. Microblading involves breaking the skin barrier, which can introduce bacteria and increase the risk of infection. Proper sterilization techniques and aftercare instructions must be followed to minimize this risk.

3. Bleeding and Healing: Patients with favism may experience issues with bleeding due to their condition. The microblading process can cause minor bleeding, and individuals with G6PD deficiency should discuss their bleeding tendencies with the practitioner. Additionally, healing times may vary, and it is essential to monitor the area for any signs of complications.

4. Consultation with Healthcare Providers: Before proceeding with microblading, it is advisable for patients with favism to consult with their healthcare provider or a dermatologist. They can provide personalized advice based on the individual's health status and any medications they may be taking.

5. Choosing a Qualified Practitioner: Selecting a skilled and experienced microblading artist is crucial. They should be informed about the patient's medical history and be able to accommodate any specific needs or concerns related to favism.

6. Post-Procedure Care: Aftercare is vital for preventing infections and ensuring proper healing. Patients should follow the aftercare instructions provided by the microblading artist and report any unusual symptoms, such as excessive redness, swelling, or discharge.

In summary, while patients with favism may be able to undergo microblading, it is essential to approach the procedure with caution. A thorough consultation with healthcare providers, careful selection of products, and adherence to safety protocols can help mitigate potential risks. Ultimately, the decision should be made collaboratively between the patient and their healthcare team, considering all factors involved.

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