Prostate Inflammation: Medication Conflicts and Usage Tips - Urology

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Prostatitis


Hello, I recently went to the hospital due to difficulty urinating and a feeling of incomplete bladder emptying.
It was found that my prostate was inflamed again.
The doctor prescribed several medications, including Tamsulosin D 0.2 mg and Rowapraxin 10 mg tablets.
I checked the contraindications for Rowapraxin, and one of them states "patients with urinary retention due to prostatic enlargement." On the other hand, the indication for Tamsulosin D is "urinary obstruction associated with benign prostatic hyperplasia," and this medication "relaxes the smooth muscles of the prostate and bladder neck." Based on the explanations I found online, it seems that there might be a conflict between the two medications.
If I have difficulty urinating and a feeling of incomplete bladder emptying while taking Rowapraxin, could this potentially reduce the effectiveness of Tamsulosin? Additionally, I would like to ask about the proper way to take Tamsulosin D.
Is it better to dissolve it in the mouth and swallow it with saliva, or to swallow the whole tablet with water? Which method would least affect the medication's efficacy?

Niming, 20~29 year old female. Ask Date: 2019/02/25

Dr. Xu Wencang reply Urology


After taking the medication, follow up at the outpatient clinic.
Tamsulosin D is an orally disintegrating tablet.

Reply Date: 2019/02/25

More Info


Understanding prostate inflammation and the medications used to treat it can be complex, especially when considering potential conflicts between different drugs. In your case, you have been prescribed Tamsulosin D and Rowapraxin for your prostate inflammation, and you are concerned about their compatibility and effectiveness.

Tamsulosin D is an alpha-1 adrenergic antagonist primarily used to treat benign prostatic hyperplasia (BPH), which is a condition characterized by an enlarged prostate that can cause urinary difficulties. Tamsulosin works by relaxing the smooth muscles in the prostate and bladder neck, which helps improve urine flow and reduce symptoms such as difficulty urinating and a feeling of incomplete bladder emptying.

On the other hand, Rowapraxin, which is a brand name for a medication that contains the active ingredient prazosin, is also used to treat urinary symptoms but has a different mechanism of action. It is important to note that Rowapraxin is contraindicated in patients with urinary retention due to prostatic enlargement. This is because it can exacerbate urinary retention, which is counterproductive for someone experiencing urinary difficulties due to prostate inflammation.

Your concern about the potential conflict between these two medications is valid. If Rowapraxin is causing urinary retention, it could indeed counteract the benefits of Tamsulosin D, which is intended to alleviate those very symptoms. Therefore, it is crucial to communicate with your healthcare provider about your concerns. They may need to reassess your medication regimen to ensure that the treatments you are receiving do not interfere with each other.

Regarding the administration of Tamsulosin D, it is important to follow the specific instructions provided by your healthcare provider or the medication packaging. Tamsulosin D is typically available as an orally disintegrating tablet, which means it is designed to dissolve in your mouth before swallowing. This method can enhance absorption and effectiveness. If the instructions specify that it should be taken with water, then it is best to follow that guidance. However, if there are no specific instructions against it, taking it as an orally disintegrating tablet is generally considered effective.

In addition to medication, lifestyle modifications can also play a significant role in managing prostate inflammation. It is advisable to maintain a balanced diet, avoid spicy and irritating foods, and stay hydrated. Regular exercise and avoiding activities that put pressure on the prostate, such as prolonged sitting or cycling, can also be beneficial.

If you continue to experience symptoms or have concerns about your medications, it is essential to follow up with your healthcare provider. They can provide personalized advice based on your medical history and current condition. Remember, managing prostate health often requires a comprehensive approach that includes both medication and lifestyle changes.

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