Is It Normal to See Suppository Residue in Stool After Hemorrhoid Treatment?

Is it normal to have hemorrhoid suppositories in the stool?

Hello, Dr.
Ko.
I recently experienced swelling and discomfort in my anus, and after visiting the hospital, I was diagnosed with internal hemorrhoids causing the swelling.
I was prescribed a two-week course of suppositories (Hiyu Zhi).
After using them for a week, the swelling and pain in my anus have indeed subsided.
However, the hospital also instructed me to undergo a stool screening, which I need to do the day after finishing the two-week course of suppositories.
I am concerned because my stool contains remnants of the suppository, and I wonder if this will affect the results.
Additionally, I have been inserting the suppository to a depth of one and a half fingers, but I am unsure why it hasn't been fully absorbed.

Mao Laoshi, 20~29 year old female. Ask Date: 2019/03/07

Dr. Ke Fangxu reply Surgery

The new immunological fecal occult blood screening method is not affected by medications and is only related to the presence or absence of red blood cells.
Suppositories may have some residual medication due to incomplete absorption, but this is not a concern.

Reply Date: 2019/03/07

More Info

It is not uncommon to see suppository residue in your stool after hemorrhoid treatment, especially if you are using a medication like "Hiyu Zhi" (a suppository for hemorrhoids). Suppositories are designed to dissolve and be absorbed by the body, but several factors can influence their absorption and effectiveness.

Firstly, the absorption of a suppository can vary based on its formulation, the individual's body temperature, and the condition of the rectal mucosa. If the suppository is not fully absorbed, it may pass through the digestive tract and appear as residue in your stool. This can happen for several reasons:
1. Insufficient Time for Absorption: If you have a bowel movement shortly after inserting the suppository, it may not have had enough time to dissolve and be absorbed. It is generally recommended to avoid having a bowel movement for at least 30 minutes after insertion to allow for optimal absorption.

2. Rectal Conditions: Conditions such as inflammation or irritation in the rectal area can affect how well a suppository is absorbed. If you are still experiencing discomfort or swelling from the hemorrhoids, this could hinder the absorption process.

3. Technique of Insertion: You mentioned inserting the suppository about one and a half fingers deep. While this is generally adequate, ensuring that it is placed correctly can help with absorption. It should be inserted past the anal sphincter to ensure it is in the rectal cavity where absorption occurs.

4. Suppository Composition: Some suppositories are made with ingredients that may not dissolve completely or may be designed to release their active ingredients slowly. If the formulation is not designed for rapid absorption, you may see residue.

Regarding your concern about the residue affecting your stool tests, it is important to follow your healthcare provider's instructions. The presence of suppository residue should not significantly impact the results of a stool test, but it is advisable to inform your doctor about the situation. They may recommend waiting a short period after finishing the suppository treatment before conducting the stool test to ensure accurate results.

In conclusion, while seeing suppository residue in your stool can be concerning, it is not necessarily indicative of a problem with the treatment itself. If you continue to experience discomfort or if the residue persists, it would be wise to consult your healthcare provider for further evaluation. They may suggest alternative treatments or adjustments to your current regimen to enhance absorption and effectiveness. Additionally, if you have any ongoing symptoms or concerns about your hemorrhoids or bowel health, do not hesitate to reach out for medical advice.

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