Mucus in Stool: Causes and When to Seek Medical Help - Gastroenterology and Hepatology

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Mucus in stool


Hello Doctor, I have been experiencing irregular menstrual cycles for a long time and have been undergoing regular check-ups.
Since November of last year, I started taking Metformin 500mg due to polycystic ovary syndrome, taking one tablet after breakfast and dinner.
Since I began taking it, I have been experiencing intermittent diarrhea, and it seems that I have not adapted as the gynecologist suggested.
Before the diarrhea, I often feel gas or intestinal motility.
Sometimes my stools are soft, and other times they are unformed.
I have a bowel movement once a day, but during diarrhea episodes, it can be 1 to 3 times a day, lasting about three to four days, which feels quite frequent.
When the stools are unformed, they do not have mucus, but afterward, the stools can be very sticky.
I am unsure if this is what is referred to as mucus stools, as the mucus seems to be mixed with the stool, and the color is similar to that of the stool.
Normal stools and soft stools do not have a mucus issue.
I have a history of follicular thyroid carcinoma and am on regular follow-up and medication.
There is no blood in the stool, I have not lost weight, and I have no issues with appetite; it seems that the mucus is the only problem, while everything else appears normal, and my menstrual cycle has also stabilized.
A fecal occult blood test two years ago was normal.
I looked up the issue of mucus in the stool, and it seems quite serious.
Before taking Metformin, my bowel movements were normal.
I am unsure if this medication truly causes such frequent diarrhea accompanied by mucus, and whether I should seek medical attention promptly.

Kong, 20~29 year old female. Ask Date: 2019/03/12

Dr. Chen Qifeng reply Gastroenterology and Hepatology


The above symptoms may be side effects of the medication.
Please consult the prescribing physician, and if necessary, seek an appointment with a gastroenterologist.

Reply Date: 2019/03/12

More Info


Understanding mucus in stool can be a complex issue, especially when it is accompanied by changes in bowel habits such as diarrhea. In your case, it seems that you have been experiencing increased bowel movements and the presence of mucus since starting the medication Metformin (伏糖), which is commonly prescribed for conditions like polycystic ovary syndrome (PCOS).
Mucus in stool can be a normal finding, as the intestines produce mucus to help lubricate the stool and facilitate its passage. However, an increase in mucus, especially when accompanied by diarrhea, can indicate an underlying issue. In your situation, the frequent diarrhea and mucus could be related to the Metformin itself, as gastrointestinal side effects are common with this medication. Many patients report symptoms such as diarrhea, abdominal cramping, and bloating when they first start taking Metformin. These symptoms often improve over time as the body adjusts to the medication, but they can be bothersome in the interim.

The presence of mucus in your stool, particularly if it is not accompanied by blood or significant weight loss, may not be immediately alarming. However, it is essential to monitor your symptoms closely. If the diarrhea persists, worsens, or if you develop additional symptoms such as fever, severe abdominal pain, or blood in your stool, it would be prudent to seek medical attention.
Given your history of thyroid follicular cancer and the ongoing monitoring you are undergoing, it is also important to consider that any new gastrointestinal symptoms should be discussed with your healthcare provider. They may want to rule out other potential causes of your symptoms, including infections, inflammatory bowel disease, or other gastrointestinal disorders.

In summary, while mucus in stool can be a benign finding, the context of your symptoms is crucial. Since you have been experiencing diarrhea and mucus since starting Metformin, it is likely related to the medication. However, if your symptoms do not improve or if you have any concerns, it is advisable to consult with your healthcare provider for further evaluation. They may recommend stool tests, dietary adjustments, or possibly a change in medication if necessary. Always prioritize open communication with your healthcare team, especially when managing multiple health conditions.

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