Does Taking Menstrual Induction Pills Affect Pregnancy? - Obstetrics and Gynecology

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Taking medication to induce menstruation in case of a delayed period can have implications if you are pregnant. It is important to avoid such medications during pregnancy, as they may pose risks to the developing fetus. If there is a possibility of pregnancy, it is advisable to take a pregnancy test and consult a healthcare professional before taking any medication?


Hello Doctor, my last menstrual period was from February 9 to February 13, with a regular cycle of 28 days.
I had unprotected intercourse on February 18, and I haven't gotten my period until March 21.
I took two home pregnancy tests, both of which were negative.
On March 23, I went to the gynecologist for a urine test and an ultrasound, which showed a 3 cm cyst, but no pregnancy was detected.
The doctor prescribed Provera 10 mg and Duphaston, to be taken three times a day after meals for three days.
If I later find out that I am pregnant, will these two medications affect the baby? Is it possible to be pregnant and still have negative test results? What causes the cyst? The doctor only told me to take the medication to induce my period and to return for a follow-up if I still haven't gotten my period by April 4, but I am still feeling very anxious.

Hui, 30~39 year old female. Ask Date: 2019/03/26

Dr. Huang Jianzhong reply Obstetrics and Gynecology


The last menstrual period was from February 9 to February 13, with a regular cycle of 28 days.
I had unprotected intercourse on February 18, and I did not get my period until March 21.
I took two home pregnancy tests, both of which were negative.
On March 23, I visited a gynecologist for a urine test and an ultrasound, which showed a 3 cm cyst.
The doctor prescribed Provera 10 mg and Duphaston, to be taken three times a day after meals for three days.
If I later find out that I am pregnant, will these two medications affect the baby? Ans: Current reports indicate that there should be no impact.
Is it possible that I am pregnant but the tests are still negative? Ans: It is unlikely.
What could be causing the cyst? Ans: The cause is unknown.
PS: The doctor only advised me to take the medication to induce menstruation and to return for a follow-up if I do not get my period by April 4, but I still feel very anxious.

Reply Date: 2019/03/26

More Info


Taking menstrual induction pills, such as Provera (medroxyprogesterone acetate), can raise concerns when it comes to early pregnancy. Provera is a synthetic form of the hormone progesterone, which is often prescribed to regulate menstrual cycles or induce menstruation in women who have irregular periods. If you suspect you might be pregnant after taking these medications, it’s understandable to feel anxious about the potential effects on the fetus.

Firstly, it’s important to note that Provera is generally considered safe during early pregnancy, but it is not recommended unless absolutely necessary. If a woman is unknowingly pregnant while taking Provera, the risk of harm to the developing fetus is relatively low, especially if the medication is taken in the early weeks of pregnancy. However, it is always best to consult with a healthcare provider for personalized advice.

The fact that you have not yet received a positive pregnancy test, despite having had unprotected intercourse, could be due to several factors. It is possible that you could still be pregnant but at a stage where the hormone levels are not yet high enough to be detected by a home pregnancy test or even by a urine test at the doctor’s office. This is particularly true if your menstrual cycle is irregular or if you have a condition affecting hormone levels.

Regarding the presence of a 3 cm cyst (referred to as a "water tumor" in your question), it is essential to understand that ovarian cysts are quite common and often harmless. They can form due to various reasons, including hormonal imbalances, and are usually functional cysts that resolve on their own. However, if the cyst is causing discomfort or other symptoms, further evaluation may be necessary.

If you are concerned about the medications you have taken and their potential impact on a possible pregnancy, it is crucial to communicate this with your healthcare provider. They can perform further tests, such as blood tests to measure hCG levels, which can provide a more accurate assessment of pregnancy status. Additionally, they can monitor the cyst and determine if any further action is needed.

In summary, while taking menstrual induction pills like Provera can cause concern if pregnancy is suspected, the risk to the fetus is generally low if the medication was taken early in the pregnancy. However, it is vital to seek medical advice to ensure both your health and the health of a potential pregnancy. If you have any further questions or concerns, do not hesitate to reach out to your healthcare provider for guidance. They can help you navigate this situation and provide the reassurance you need.

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