Menstrual Delay Medications: What You Need to Know - Obstetrics and Gynecology

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Issues with menstrual regulation medications?


I recently need to undergo a health check-up, so to avoid my menstrual period, my doctor prescribed Lybrel (which is pink with a triangular design) to delay my period.
I took it for 7 days before bedtime.
I looked up the ingredients online, which are: 1.
Norethindrone Acetate 2.
Ethinyl Estradiol.
My last menstrual cycle has been 42 days, while my usual cycle is about 30 to 33 days.
However, my menstrual cycle has been somewhat irregular for the past four months.
I had an ultrasound in early March, and the doctor found no abnormalities, so I believe it is due to hormonal instability.
Will delaying my period with this medication cause my cycle to become significantly longer than usual? As long as my period still comes, is that acceptable? Are there any specific concerns I should be aware of? Thank you, doctor.

EE, 20~29 year old female. Ask Date: 2019/04/11

Dr. Cao Guotao reply Obstetrics and Gynecology


Hello, after taking the emergency contraceptive pill, menstruation typically occurs in about four days.
If your menstrual cycle was normal prior to this and has only been irregular for the past four months, it is advisable to monitor your cycle for one to two months.
If it remains irregular, I recommend consulting a gynecologist for hormone level testing.
Wishing you good health.

Reply Date: 2019/04/11

More Info


When it comes to understanding medications prescribed for menstrual delay, such as the one you mentioned (likely a combination of Norethindrone Acetate and Ethinyl Estradiol), it’s essential to grasp both the pharmacological aspects and the implications for your menstrual cycle.


Overview of the Medication
1. Norethindrone Acetate: This is a synthetic progestin, which mimics the effects of the hormone progesterone. It is often used in various hormonal therapies, including those for menstrual regulation, contraception, and treatment of endometriosis. In the context of delaying menstruation, it works by stabilizing the endometrial lining and preventing the shedding that occurs during a typical menstrual cycle.

2. Ethinyl Estradiol: This is a synthetic form of estrogen, commonly used in combination with progestins in oral contraceptives. It helps regulate the menstrual cycle and can enhance the effectiveness of progestins in controlling menstrual bleeding.


Purpose of the Medication
The primary purpose of prescribing this combination medication is to delay menstruation for a specific period, which can be particularly useful for individuals who have upcoming events or medical examinations. By taking the medication as directed (in your case, for 7 days), you can effectively postpone your period.


Understanding Your Menstrual Cycle
You mentioned that your menstrual cycle has been somewhat irregular over the past few months, with a typical cycle length of 30-33 days but currently extending to 42 days. Irregular cycles can be influenced by various factors, including hormonal imbalances, stress, weight changes, and underlying health conditions. The fact that you had an ultrasound that showed no abnormalities is reassuring, but it’s still important to monitor your cycle closely.


Potential Effects of Delaying Menstruation
1. Cycle Length: It’s not uncommon for the use of hormonal medications to alter your cycle length temporarily. After stopping the medication, your body may take some time to readjust, and your cycle may return to its usual pattern. However, it’s also possible for it to take a few cycles for your body to stabilize.

2. Menstrual Symptoms: Some individuals may experience side effects from hormonal medications, including mood swings, breast tenderness, nausea, or changes in weight. If you notice any severe or concerning symptoms, it’s essential to consult your healthcare provider.

3. Return of Menstruation: As long as you eventually have a menstrual period after stopping the medication, it is generally considered normal. However, if your period does not return within a reasonable timeframe (usually a few weeks after stopping the medication), or if you experience any unusual symptoms (such as severe pain or heavy bleeding), you should seek medical advice.


Important Considerations
- Monitoring: Keep track of your menstrual cycle after stopping the medication. Note any changes in flow, duration, or associated symptoms.

- Consultation: If you have concerns about your cycle length or any side effects from the medication, don’t hesitate to reach out to your healthcare provider. They can provide personalized advice based on your medical history and current health status.

- Lifestyle Factors: Consider lifestyle factors that might be contributing to hormonal imbalances, such as stress management, diet, exercise, and sleep patterns.

In summary, while delaying your period with medications like Norethindrone Acetate and Ethinyl Estradiol can be effective, it’s crucial to monitor your body’s response and maintain open communication with your healthcare provider. This will help ensure that any potential issues are addressed promptly and that your menstrual health is managed effectively.

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