HPV: Questions About Warts and Follow-Up Care - Obstetrics and Gynecology

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Hello, a month ago I was diagnosed with genital warts and have been undergoing treatment for four weeks.
Currently, I don't see the initial white bumps anymore, but there is a small pink raised area below the vaginal opening that is the same color as the surrounding skin.
It feels soft and does not have the hard texture typical of warts, so could it just be a natural bump that was already there? Additionally, when I insert my fingers deep into the vagina, I can feel some wrinkled, granular tissue at the base, but I'm unsure if this is part of the normal anatomy.
Could this be warts?
Furthermore, I would like to ask what a patient with genital warts should do after three months without symptoms.
Besides testing for HIV, should I also have regular Pap smears and receive the HPV vaccine? Thank you.

Az, 20~29 year old female. Ask Date: 2019/04/26

Dr. Huang Jianzhong reply Obstetrics and Gynecology


A month ago, I was diagnosed with genital warts and have been undergoing treatment for four weeks.
Currently, I don't see the initial white bumps, but there is a small pink protrusion at the vaginal opening that matches the surrounding color.
It doesn't feel hard like warts; could it just be a natural bump that was already there?
Answer: It's possible.
When I inserted my fingers deep into the vagina, I felt a wrinkled, granular texture at the base, but I'm not sure if it's part of the normal anatomy.
Could this be warts?
Answer: A visual examination is needed.
Additionally, I would like to ask what a patient with warts should do after three months without symptoms.
Besides testing for HIV, should I also have regular Pap smears and receive the HPV vaccine?
Answer: Yes.

Reply Date: 2019/04/26

More Info


Human Papillomavirus (HPV) is a complex virus with over 200 different types, some of which are classified as low-risk and others as high-risk. Low-risk types, such as HPV 6 and 11, are commonly associated with benign conditions like genital warts (also known as condylomata acuminata), while high-risk types, such as HPV 16 and 18, are linked to various cancers, including cervical cancer.


Understanding HPV Transmission and Infection
1. Transmission: HPV is primarily transmitted through direct skin-to-skin contact, particularly during sexual activity. It is not congenital, meaning it is not passed from mother to child during childbirth. While most HPV infections are transient and resolve spontaneously due to the immune system's response, some individuals may experience persistent infections, particularly with high-risk types, which can lead to precancerous lesions or cancer over time.

2. Different Types and Their Impact: The risk of developing health issues from HPV varies significantly among its different types. For instance, while HPV 6 and 11 are responsible for most genital warts, high-risk types like HPV 16 and 18 are responsible for the majority of cervical cancer cases. The viral load (the amount of virus present) can influence the likelihood of developing symptoms or disease, but even low viral loads can be infectious.

3. Asymptomatic Transmission: It is important to note that HPV can be transmitted even when there are no visible symptoms or lesions. This means that individuals with HPV may unknowingly spread the virus to their partners. Regular screenings and vaccinations are crucial for prevention and early detection.


Follow-Up Care for HPV Patients
For individuals diagnosed with HPV-related conditions, such as genital warts or precancerous lesions, follow-up care is essential:
1. Monitoring and Screening: After treatment for genital warts, it is recommended to have regular follow-ups. For women, this includes Pap smears and HPV testing, as these can help detect any changes in cervical cells that may indicate precancerous conditions. The frequency of these tests can vary based on individual risk factors and previous results.

2. Vaccination: The HPV vaccine is highly effective in preventing infections from the most common high-risk types of HPV. Even if someone has been diagnosed with HPV, vaccination can still provide protection against other types they may not have been exposed to yet.

3. Self-Examination and Awareness: Patients should be educated on self-examination techniques and be aware of any changes in their genital area. If new growths or changes occur, they should seek medical advice promptly.

4. Lifestyle Considerations: Maintaining a healthy lifestyle can support the immune system in clearing HPV. This includes a balanced diet, regular exercise, and avoiding smoking, which can compromise immune function.


Addressing Specific Concerns
Regarding your specific questions about the small pink bump and the wrinkled texture you felt, it is essential to consult with a healthcare provider for an accurate diagnosis. The presence of a small bump does not necessarily indicate a recurrence of warts, as normal anatomical variations can exist.
If you have been treated for genital warts and are asymptomatic, it is still advisable to continue with regular screenings and follow-up appointments. The HPV vaccine can be beneficial even after a diagnosis, as it protects against other strains of the virus.

In summary, understanding HPV involves recognizing its modes of transmission, the implications of different types, and the importance of follow-up care. Regular screenings, vaccinations, and maintaining a healthy lifestyle are key components in managing HPV and reducing the risk of associated health issues. Always consult with a healthcare professional for personalized advice and treatment options.

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