Managing Menopause: Hormone Therapy Options and Concerns - Obstetrics and Gynecology

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Hormone Replacement Therapy for Menopause


Hello, Doctor: I am nearing menopause and experiencing menopausal symptoms such as hot flashes and insomnia.
Last year, my doctor recommended taking a plant-based hormone called "Fujabao," which I have been taking for a year.
Recently, during a visit to the gynecology clinic for a Pap smear, the doctor mentioned that I have a severe hormone deficiency and prescribed "Premarin vaginal cream" as well as oral "Vivelle-Dot" tablets.
I would like to know if it is necessary to use both treatments simultaneously since my menopausal symptoms are currently manageable.
I am also concerned about the potential risk of hormone therapy leading to breast cancer.
If I choose not to use any hormone treatments, what impact could that have on my health? Thank you for your guidance!

Li, 40~49 year old female. Ask Date: 2019/05/20

Dr. Zhang Kunmin reply Obstetrics and Gynecology


Hello, the treatment involving hormonal components does not need to be repeated and can be chosen after discussion with the treating physician.
A deficiency in hormones can lead to menopausal symptoms and conditions such as osteoporosis.
The risk of breast cancer should be assessed based on the patient's individual characteristics.
It is recommended to provide relevant medical history and risk factors to the prescribing physician to determine suitability, while also adhering to regular breast screenings.
Thank you! Wishing you peace and health, Dr.
Zhang.

Reply Date: 2019/05/20

More Info


Managing menopause can be a complex process, especially when considering hormone therapy (HT) options and the associated risks and benefits. As you approach menopause, it is common to experience symptoms such as hot flashes, night sweats, and sleep disturbances. These symptoms can significantly impact your quality of life, and many women seek relief through various treatments, including hormone therapy.

In your case, you mentioned that you have been using a plant-based hormone supplement, "Fujabao," for a year, which has helped with your symptoms. However, after a recent visit to your gynecologist, you were prescribed "Prilmarin vaginal cream" and "Vinina tablets" due to severe hormone deficiency. This raises the question of whether it is necessary to use both treatments simultaneously and what the implications of hormone therapy might be, particularly concerning breast cancer risk.

Firstly, it is essential to understand that hormone therapy can be beneficial for managing menopausal symptoms. Estrogen therapy, whether systemic (like pills or patches) or localized (like vaginal creams), can help alleviate symptoms such as hot flashes and vaginal dryness. The addition of progesterone (as in Vinina tablets) is typically recommended for women who still have their uterus to protect against endometrial hyperplasia, which can occur with unopposed estrogen therapy.

Regarding your concern about using both treatments at the same time, it is not uncommon for healthcare providers to prescribe a combination of therapies to address different aspects of hormone deficiency. The vaginal cream can provide localized relief for vaginal symptoms, while the oral medication can help with systemic symptoms. However, the decision to use both should be made in consultation with your healthcare provider, who can assess your specific symptoms, medical history, and any potential risks.

The concern about hormone therapy and breast cancer risk is valid. Research has shown that long-term use of combined estrogen and progestin therapy may increase the risk of breast cancer, particularly in women who have a family history of the disease or other risk factors. However, the risk is generally considered to be low for women who use hormone therapy for a short duration (typically less than five years) and who do not have other significant risk factors. It is crucial to have an open discussion with your doctor about your personal risk factors and the potential benefits and risks of hormone therapy.

If you choose not to use hormone therapy, you may experience continued menopausal symptoms, which can affect your quality of life. Non-hormonal options are available, including lifestyle modifications (such as diet and exercise), alternative therapies (like acupuncture or herbal supplements), and non-hormonal medications (such as SSRIs or gabapentin) that can help manage hot flashes and mood changes. However, these alternatives may not be as effective as hormone therapy for some women.

In conclusion, managing menopause and deciding on hormone therapy requires careful consideration of your symptoms, medical history, and personal preferences. It is essential to work closely with your healthcare provider to determine the best approach for you, whether that involves hormone therapy, non-hormonal options, or a combination of treatments. Regular monitoring and open communication about your symptoms and any side effects will help ensure that you receive the most appropriate care during this transitional phase of life.

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