Gastric Polyps: Types, Pathology, and Mild Dysplasia Explained - Gastroenterology and Hepatology

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Gastric gland polyps with localized mild cellular atypia?


Hello, doctor.
I recently received my gastroscopy report, which states: gastric polyps measuring 0.3-0.6 cm, polypectomy performed, and the pathology report indicates gastric fundic gland polyps with focal mild dysplasia, benign lesion.
I would like to ask whether my polyps are classified as fundic gland polyps, hyperplastic polyps, or something else? If it is something else, what is it? Also, what does "focal mild dysplasia" mean? Thank you.

Liú, 30~39 year old female. Ask Date: 2019/06/12

Dr. Chen Qifeng reply Gastroenterology and Hepatology


Such a report can be regarded as a benign lesion.

Reply Date: 2019/06/12

More Info


Understanding gastric polyps is crucial for effective management and monitoring of gastrointestinal health. Based on your recent endoscopy report, it appears that you have gastric polyps measuring between 0.3 to 0.6 cm, which were removed and analyzed. The pathology report indicates that these polyps are classified as fundic gland polyps with areas of mild dysplasia.


Types of Gastric Polyps
1. Fundic Gland Polyps: These are the most common type of gastric polyps, typically associated with the use of proton pump inhibitors (PPIs) and are generally considered benign. They arise from the gastric fundus and contain dilated foveolar glands and parietal cells. Your report suggests that your polyps fall into this category.

2. Hyperplastic Polyps: These are usually associated with chronic gastritis and are also benign. They can occur in response to inflammation and are often found in the antrum of the stomach.

3. Adenomatous Polyps: These are considered precursors to gastric cancer and can exhibit dysplasia. They are less common than fundic gland and hyperplastic polyps.

4. Malignant Polyps: These are rare and indicate the presence of cancerous cells.


Mild Dysplasia Explained
The term "mild dysplasia" refers to the presence of abnormal cells that have not yet developed into cancer. Dysplasia is a term used to describe changes in the size, shape, and organization of cells. Mild dysplasia indicates that while there are some changes in the cells, they are not severe enough to be classified as cancerous. This condition is often a precursor to more serious changes, but it does not mean that cancer is present.


Clinical Implications
1. Monitoring: Since your polyps are classified as fundic gland polyps with mild dysplasia, they are generally considered benign. However, the presence of dysplasia means that regular monitoring is essential. Your healthcare provider may recommend follow-up endoscopies to ensure that the polyps do not progress or change.

2. Management: If you are on PPIs, it may be worth discussing with your physician whether you should continue this medication, as long-term use can lead to the development of fundic gland polyps. Additionally, lifestyle modifications such as dietary changes, reducing alcohol intake, and quitting smoking can contribute to overall gastric health.

3. Further Investigation: If there are concerns about the nature of the polyps or if there are changes in your symptoms, your doctor may recommend additional testing, such as imaging studies or more frequent endoscopies.

4. Family History and Risk Factors: If there is a family history of gastric cancer or polyps, it may be prudent to discuss genetic counseling or more aggressive surveillance strategies with your healthcare provider.


Conclusion
In summary, your gastric polyps are likely fundic gland polyps with mild dysplasia, which are generally benign but warrant monitoring. It is essential to maintain regular follow-ups with your gastroenterologist to track any changes in your condition. If you have further questions or concerns about your diagnosis or management plan, do not hesitate to reach out to your healthcare provider for personalized advice.

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