Medication Abortion: Timing and Safety Concerns - Obstetrics and Gynecology

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Medication abortion


My girlfriend went to the hospital for a medical abortion.
On the morning of June 27, she took the first dose of three pills.
She said the doctor informed her to take the remaining three pills on the evening of June 28.
However, I researched online and found that the remaining three pills are usually taken 36 to 48 hours later.
I'm concerned whether taking them this way could be too much for her body, whether it might cause more harm during the abortion, and whether it will be successful.

Ga Gu, 20~29 year old female. Ask Date: 2019/06/28

Dr. Lin Manying reply Obstetrics and Gynecology


Hello, sir: Regarding the administration of RU486, there are several protocols.
This is one of them; please continue to follow your doctor's advice and return for follow-up appointments.
Hualien Hospital, Ministry of Health and Welfare, cares about your health.

Reply Date: 2019/06/28

More Info


Medication abortion, also known as medical abortion, is a safe and effective method for terminating a pregnancy using medication. It typically involves a two-step process using two different medications: mifepristone and misoprostol. Understanding the timing and safety concerns associated with this process is crucial for ensuring the health and well-being of the individual undergoing the procedure.

In your girlfriend's case, it appears she took the first dose of medication on June 27th, which is the mifepristone. This medication works by blocking the hormone progesterone, which is necessary for the pregnancy to continue. After taking mifepristone, it is standard practice to wait 24 to 48 hours before taking the second medication, misoprostol. Misoprostol is taken to induce contractions and expel the pregnancy tissue from the uterus.

The timing of taking misoprostol is indeed important. While some healthcare providers may recommend taking it as soon as 24 hours after mifepristone, others may advise waiting up to 48 hours. The recommendation can vary based on individual circumstances and the healthcare provider's protocol. If your girlfriend was instructed to take the second set of pills on the evening of June 28th, this falls within the typical timeframe, assuming she took the first dose on the morning of June 27th.

Regarding safety concerns, medication abortion is generally very safe when done according to medical guidelines. Side effects can include cramping, bleeding, nausea, vomiting, diarrhea, and fatigue, which are all normal reactions to the medications. However, if the timing of the doses is not followed as recommended, it could potentially lead to complications or an incomplete abortion, which may require further medical intervention.

It is essential for your girlfriend to follow the instructions given by her healthcare provider closely. If there are any uncertainties or concerns about the timing of the medication or the process itself, it is advisable for her to contact her healthcare provider for clarification. They can provide specific guidance based on her medical history and the details of her situation.

In terms of the effectiveness of the medication abortion, studies have shown that when the medications are taken as directed, the success rate is over 95%. However, if there are any complications or if the abortion does not occur as expected, follow-up care is crucial. This may include a follow-up appointment with a healthcare provider to ensure that the abortion was complete and to address any potential complications.

In summary, medication abortion is a safe and effective method when followed correctly. The timing of taking the second medication is important, and if your girlfriend has been instructed to take it within the recommended timeframe, it should not pose a significant risk to her health. However, if there are any concerns about the process or her health, she should reach out to her healthcare provider for further guidance and support.

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