Should You Just Monitor Nasal Tumors? Insights on Lung Infiltration Concerns - Otolaryngology

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Is it sufficient to just observe an intranasal tumor? Additionally, what about the issue of pulmonary infiltration?


On June 6th, I was concerned about occasionally having very yellow nasal discharge, which I suspected was due to sinusitis, so I went to Taipei Veterans General Hospital for a nasal endoscopy.
At that time, the doctor mentioned that there was something abnormal, and a biopsy was performed.
The pathological diagnosis indicated benign nasopharyngeal mucosa from the left nasopharynx.
The gross findings showed that the specimen received in formalin was labeled as left nasopharynx, consisting of a piece of gray-white soft tissue measuring 0.3 x 0.3 x 0.1 cm.
The entire specimen was embedded in a block (H&E).
The microscopic findings revealed nasopharyngeal mucosa with lymphoid hyperplasia, and there was no evidence of malignancy identified under CK stain.
On the day of the biopsy, the attending physician mentioned that if it was benign, it might not require treatment.
However, the following week, upon reviewing the report, the doctor asked, "Don't you think it's strange that it's growing there?" The doctor also noted that the biopsy might not have captured the entire lesion, suggesting that removal might provide more peace of mind.

On July 5th, I consulted with Dr.
Lan Min-Ying from the ENT department at Taipei Veterans General Hospital.
After examining me with the nasal endoscope, she reassured me that there were no changes and advised me to not worry.
She ordered an Epstein-Barr virus test, likely because she had just performed the nasal endoscopy, and suggested that I return for a follow-up in a month for a laryngoscopy.
Additionally, I had been coughing for two months; I usually do not cough much, but when I do, it is uncontrollable (I have a history of gastroesophageal reflux disease).
I also consulted the infectious disease department (as I couldn't get an appointment with the pulmonology department), where I underwent chest X-rays, inflammatory markers, liver function tests, and other evaluations, all of which were normal.
The doctor noted slight pulmonary infiltration.
I had previously been diagnosed with mild asthma but do not typically use an inhaler.
After listening to my lungs, the doctor prescribed an inhaler, which seemed to improve my symptoms.
Based on the above, I have the following questions:
1.
Is it sufficient to just observe the lymphoid hyperplasia in the nasal cavity? If the biopsy shows no growth after one month, can I be reassured? Or is it better to remove it, since the attending physician mentioned that surgery was not necessary?
2.
I found online that pulmonary infiltration can be a serious issue, but the infectious disease doctor (also from Taipei Veterans General Hospital) seemed to think that since my inflammatory markers and white blood cell counts were normal (he tested many parameters), the infiltration was merely a general description and held no particular significance.
Is this really the case, or should I seek a consultation with a pulmonologist?
Thank you for your guidance, doctor.

xing fu, 30~39 year old female. Ask Date: 2019/07/08

Dr. Ji Zhaoyun reply Otolaryngology


Hello, based on your description:
1.
For lymphoid hyperplasia in the nasal cavity, is it sufficient to just observe? If a biopsy shows no growth after one month, can we be reassured? -> If it is nasopharyngeal lymphoid hyperplasia, it typically grows from deeper layers, and complete excision is generally not necessary.
Moreover, it cannot be completely removed, and cutting too deep could potentially damage blood vessels, leading to significant bleeding.
It is recommended to follow up with an otolaryngologist every six months to a year, and if there are any changes, then a biopsy can be performed.
2.
I found online that pulmonary infiltration is a serious matter, but the infectious disease doctor (from the same hospital) thinks my inflammatory markers and white blood cell counts are normal (he tested many indices).
He mentioned that infiltration is just a general term and has no specific significance.
Is this really the case, or should I consult a pulmonologist? -> For this question, it is advisable to consult a pulmonologist for further evaluation.
Wishing you peace, health, and well-being.

Sincerely,
Dr.
Chi Chao-Yun, Director of the Department of Otolaryngology, Taichung Hospital, Ministry of Health and Welfare.

Reply Date: 2019/07/08

More Info


When it comes to managing nasal tumors and lung infiltration concerns, a careful and systematic approach is essential. Based on the information provided, let's address your questions regarding the benign nasal tumor and the lung infiltration findings.


Monitoring Nasal Tumors
1. Observation of Nasal Lymphoid Hyperplasia:
The biopsy results indicate that the tissue from the left nasopharynx shows benign nasopharyngeal mucosa with lymphoid hyperplasia and no evidence of malignancy. In cases like this, where the tumor is small (0.3 cm) and benign, the standard approach is often to monitor rather than immediately proceed with surgical intervention. The rationale behind this is that many benign lesions, especially those that are asymptomatic and stable in size, do not require surgical removal.
Your ENT specialist has suggested a follow-up in a month, which is a reasonable approach. If there are no changes in size or symptoms, continued observation may be warranted. However, if you notice any changes, such as increased size, pain, or other symptoms, it would be prudent to revisit the decision for surgical intervention.
2. Concerns About the Biopsy:
It is understandable to feel anxious about whether the biopsy adequately captured the lesion. However, the fact that the pathologist did not find any malignancy is reassuring. If there are still concerns about the completeness of the biopsy or if the lesion changes, discussing the possibility of a repeat biopsy or imaging studies with your doctor could provide additional peace of mind.


Lung Infiltration Concerns
1. Understanding Lung Infiltration:
The term "lung infiltration" can indeed be concerning, but it is essential to interpret this finding in the context of your overall health and the results of other tests. The fact that your inflammatory markers and white blood cell counts are normal suggests that there is no acute infection or significant inflammatory process occurring. Lung infiltration can be a nonspecific term that may refer to various conditions, including infections, inflammatory diseases, or even benign processes.
Given that your symptoms have improved with treatment and that your imaging studies have not indicated any active lesions, it may not be as severe as it initially sounds. However, if you continue to experience symptoms such as persistent cough or changes in sputum, it would be wise to follow up with a pulmonologist for further evaluation.

2. When to Consult a Pulmonologist:
If your symptoms persist or worsen, or if you have concerns about the lung infiltration, it would be appropriate to consult a pulmonologist. They can provide a more detailed assessment, which may include additional imaging or pulmonary function tests to evaluate your lung health comprehensively.


Conclusion
In summary, for the nasal tumor, monitoring is a valid approach given the benign nature of the findings. Regular follow-ups with your ENT specialist will help ensure that any changes are promptly addressed. Regarding the lung infiltration, while it is essential to remain vigilant, the current findings do not suggest an immediate cause for alarm, especially with normal inflammatory markers. If symptoms persist, seeking further evaluation from a pulmonologist would be beneficial.
Always remember that your healthcare providers are there to support you, and do not hesitate to voice your concerns during follow-up appointments. Your health and peace of mind are paramount.

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