High-Risk HPV: Key Insights for Men and Safe Practices - Urology

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High-risk HPV infection


Hello, doctor.
I am a male, and I recently underwent HPV typing tests, which revealed that I am infected with HPV type 53.

1.
Aside from getting the cervical cancer vaccine and practicing safe sex, what other recommendations do you have for me? For example, how long should I wait before getting re-tested?
2.
Can HPV genotyping tests detect latent viruses? Does "latent period" refer to the time from exposure to the virus until a positive test result, or from exposure to the virus until the onset of disease (such as warts or cancerous lesions)?
3.
If I manage to clear the virus through my body's immune response, is there still a chance I could transmit it to my partner if we engage in unprotected sex afterward?
4.
If I were infected with HPV type 16 but have since recovered, would receiving the cervical cancer vaccine afterward provide me with renewed protection against HPV type 16?
5.
The latency period for high-risk HPV can last for several years, even a lifetime, but most people can clear the virus within two years.
Can it be understood that if someone has not engaged in sexual activity for over two years, they are unlikely to test positive for HPV?
6.
I have not had sexual intercourse with anyone for ten years, and I always used condoms during previous sexual encounters.
What can you infer from this? Does it suggest a higher likelihood of environmental transmission, or does it indicate that my body has not cleared the virus over the past decade? After all, HPV is primarily transmitted through sexual contact, and the chances of environmental transmission are very low.
This is the question that confuses me the most, and I am concerned about potentially harming my new girlfriend.
I would greatly appreciate your answers to my questions.
Thank you.

Rong, 30~39 year old female. Ask Date: 2019/07/13

Dr. Du Shixi reply Urology


Hello:
1.
Besides getting the cervical cancer vaccine and practicing safe sex, what other recommendations do you have for me? For example, how often should I get checked? --> Every six months to a year.

2.
Can HPV genotyping tests detect latent viruses? Does "latent period" refer to the time from exposure to the virus until a positive test result, or from exposure to the virus until the onset of disease (such as warts or cancerous changes)? It should not be able to; you need to ask the testing facility, as different testing machines may have different capabilities.

3.
Assuming I have cleared the virus through my own immune response, is there a chance I could transmit it to my partner if I engage in unprotected sex afterward? No.

4.
If I was infected with HPV type 16 but have since recovered, will getting the cervical cancer vaccine afterward provide me with renewed protection against HPV type 16? --> It should, but there are over 100 types of HPV, and the vaccine only protects against a few types and is not 100% effective.
Please note that the vaccine is approved for use in individuals aged 9 to 26.

5.
The latency period for high-risk HPV can last for several years, even a lifetime, but most people can clear the virus within two years.
Can it be understood that if someone has not had sexual intercourse for over two years, theoretically, they would most likely not test positive for HPV? --> This applies to those who can clear the virus; not everyone can.

6.
I have not engaged in sexual activity with anyone for ten years, and I always used condoms during previous sexual encounters.
What can the doctor infer from this? Does it suggest a higher likelihood of infection from the environment, or has my body taken ten years to clear the virus? After all, HPV is primarily transmitted through sexual contact, and the chance of environmental transmission is very low.
This is what I find most confusing.
--> HPV cannot be completely prevented through safe sex practices alone.
Additionally, warts can develop on other parts of the body, such as the soles of the feet or hands, which are also caused by HPV.
Therefore, the area you tested positive for may not definitively indicate the source of the infection.
However, I am very concerned about potentially harming my new girlfriend, so I kindly ask the doctor to answer my questions.
Thank you.

Reply Date: 2019/07/13

More Info


Understanding High-Risk HPV: Key Insights for Men and Safe Practices
Human Papillomavirus (HPV) is a common sexually transmitted infection that can affect both men and women. High-risk HPV types, such as HPV 16 and 53, are associated with various cancers, including cervical cancer in women and other anogenital cancers in men. If you have recently tested positive for HPV 53, it is essential to understand the implications and the best practices for managing your health and protecting your partner.

1. Recommendations Beyond Vaccination and Safe Sex: While vaccination against HPV is crucial, maintaining a healthy lifestyle can also support your immune system in managing the virus. This includes eating a balanced diet rich in fruits and vegetables, exercising regularly, managing stress, and getting adequate sleep. Regular check-ups with your healthcare provider are essential. Depending on your doctor's advice, you may want to schedule follow-up HPV testing every 6 to 12 months to monitor your status.

2. Understanding HPV Testing and Latency: HPV testing can detect the presence of the virus, but it does not indicate the exact timing of infection. The latency period refers to the time from exposure to the virus until it can be detected in a test. This can range from a few weeks to several years. The latency period can also refer to the time it takes for the virus to cause symptoms or lead to disease, which can take years. Therefore, if you test positive, it does not necessarily mean you were recently infected.

3. Clearing the Virus and Transmission Risks: If your immune system successfully clears the HPV infection, the risk of transmitting the virus to your partner is significantly reduced. However, it is important to note that HPV can sometimes remain dormant in the body. Engaging in unprotected sex after clearing the virus may still carry a risk of transmission if the virus reactivates. Therefore, it is advisable to maintain safe sex practices, including the use of condoms, even if you believe you have cleared the virus.

4. Vaccination After Infection: If you have previously been infected with HPV 16 and have cleared the infection, receiving the HPV vaccine can still provide protection against future infections of the same type. The vaccine works by stimulating the immune system to recognize and fight the virus, potentially offering renewed protection against strains you may have been exposed to in the past.

5. Understanding HPV Persistence: It is true that many individuals can clear HPV infections within two years. However, if you have not engaged in sexual activity for an extended period, it is possible that you may still test positive for HPV due to a previous infection that your body has not yet cleared. The likelihood of being HPV positive after a long period without sexual contact can suggest either a persistent infection or a very low risk of re-infection from environmental sources, which is rare.

6. Interpreting Your Sexual History: Given your history of consistent condom use and a long period without sexual partners, it is more likely that your HPV infection is a result of a past exposure rather than a new infection. HPV is primarily transmitted through skin-to-skin contact during sexual activity, and while environmental transmission is theoretically possible, it is exceedingly rare. Your situation suggests that the virus may have remained dormant in your system for years.

In conclusion, managing HPV involves a combination of vaccination, safe sexual practices, and regular health check-ups. Communicating openly with your partner about your HPV status is essential for mutual understanding and safety. If you have concerns about your health or the implications for your relationship, consider consulting a healthcare provider who specializes in sexual health for personalized advice and support.

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