Interaction issues
Is there an interaction between ginkgo biloba extract and nutmeg PCA (a facial cleanser ingredient)? Can ginkgo biloba extract 120 mg be used on the same day as a scar cream containing sodium heparin? If so, how long should the interval be between applications? Thank you.
Niming, 30~39 year old female. Ask Date: 2019/08/17
Dr. Hou Fangmin reply Pharmacology
Hello, Sir:
1.
Is there an interaction between Ginkgo biloba extract and nutmeg PCA (a component in facial cleansers)? Answer: Nutmeg has astringent properties that can alleviate diarrhea, has sedative and hypnotic effects, possesses antibacterial and anesthetic properties, treats scars, and promotes blood circulation.
Ginkgo biloba is effective in improving cardiovascular health and vascular circulation, as well as enhancing myocardial ischemia, memory, and brain function.
There is no interaction between the two.
2.
Can Ginkgo biloba extract 120mg be used on the same day as a scar cream containing sodium heparin? Ginkgo biloba increases cerebral blood flow and inhibits platelet aggregation.
Ginkgo biloba products can suppress blood coagulation by activating platelets, making it difficult for blood to clot.
Therefore, it is not advisable to use it in conjunction with anticoagulants such as clopidogrel, aspirin, or heparin, as this may increase the risk of bleeding.
3.
However, since it is for external use, it is still better not to use them together, as topical applications can still be absorbed.
Is this response acceptable to you? Wishing you good health.
Reply Date: 2019/08/17
More Info
When considering the interactions between Ginkgo Biloba extract and Nutmeg PCA (which is often used in skincare products), it's important to understand both the pharmacological properties of these substances and their potential effects when used together.
Ginkgo Biloba is a herbal supplement commonly used for its potential cognitive benefits and its ability to improve blood circulation. It is known to have antioxidant properties and may help with memory enhancement and cognitive function. However, Ginkgo can also have blood-thinning effects, which is a crucial consideration if you are taking other medications or supplements that affect blood coagulation.
Nutmeg PCA, on the other hand, is primarily used in cosmetic formulations for its fragrance and potential skin benefits. While nutmeg itself has some anti-inflammatory properties, it is generally considered safe for topical use. However, it can cause skin irritation in some individuals, especially when used in high concentrations or on sensitive skin.
Regarding the interaction between Ginkgo Biloba and Nutmeg PCA, there is limited research specifically addressing their combined use. Generally, the risk of significant interactions between these two substances is low, particularly when one is used topically (Nutmeg PCA) and the other is taken orally (Ginkgo Biloba). However, individual reactions can vary, and it is always wise to monitor for any unusual side effects when combining supplements and topical products.
As for the use of Ginkgo Biloba extract (120 mg) alongside a scar treatment cream containing heparin sodium, there are no known direct interactions between Ginkgo and heparin. Heparin is an anticoagulant used to prevent blood clots, and while Ginkgo also has blood-thinning properties, the topical application of heparin in a cream is unlikely to lead to systemic effects that would be influenced by Ginkgo. However, since both substances can affect blood clotting, it is advisable to consult with a healthcare provider before using them together, especially if you have any underlying health conditions or are taking other medications.
If you decide to use both products on the same day, it is generally recommended to space them out to minimize any potential for irritation or interaction. A good rule of thumb would be to apply the topical product (heparin cream) and then wait at least 1 to 2 hours before taking the Ginkgo Biloba supplement. This allows your body to process the topical application without interference from the oral supplement.
In summary, while there is no strong evidence suggesting significant interactions between Ginkgo Biloba and Nutmeg PCA, or between Ginkgo and heparin sodium in topical applications, it is always best to err on the side of caution. Consult with a healthcare professional for personalized advice, especially if you have any pre-existing conditions or are taking other medications. Monitoring your body's response when using these products together is essential, and if you experience any adverse effects, discontinue use and seek medical advice.
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