Can People with Favism Safely Use These Medications and Essential Oils? - Pharmacology

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Can the following medications be used for G6PD deficiency?


Since the newborn screening indicated that I have G6PD deficiency, I have not undergone any further testing.
Therefore, I am unsure whether I can use or continue using the following medications/oils.
I would appreciate your guidance on the following:
1.
Menthol Cone "C.H.": I use this menthol stick for motion sickness, applying it to my philtrum, temples, and behind my ears whenever I travel.
I haven't experienced any issues so far, but I've read that individuals with G6PD deficiency should avoid menthol.
Can I continue using it? Could it lead to severe anemia?
2.
Mentholatum AD Ointment: I apply this ointment for injuries or skin eczema due to its anti-itch and slightly numbing effects, which I find very effective.
Currently, I don't seem to have any symptoms related to G6PD deficiency.
Should I continue using it? If not, what alternative products can I use for treating wounds besides this ointment?
3.
Rosemary Essential Oil: Can this essential oil be used after dilution, or should it be completely avoided? (I use it on my scalp.) (Ingredients: Rosmarinus officinalis† (Rosemary) leaf oil† 100% pure essential oil)
4.
Johnson's Baby Lavender Lotion: I usually apply this lotion before bed.
Recently, I noticed that individuals with G6PD deficiency should avoid certain scents, such as menthol, lavender, and rosemary.
Since this lotion is designed for babies, is it safe for me to use? If not, does having G6PD deficiency mean I should completely avoid scents like menthol, lavender, rosemary, and sage? If someone in my vicinity uses lavender candles or perfumes, is it unavoidable? (After all, lavender is a common scent found in various skincare products and even sanitary products.)
I have a history of anemia, irritable bowel syndrome, occasional arrhythmias, and tachycardia, so I am uncertain if these symptoms are exacerbated by G6PD deficiency or if using the above products might have an impact.
I am quite confused and turned to this website to seek your advice, as I am unsure where else to inquire.
Thank you for your patience in reading my questions and for your response.

Sang, 20~29 year old female. Ask Date: 2019/08/21

Dr. Hou Fangmin reply Pharmacology


Hello, Ms.
Sang: Can the following medications be used for G6PD deficiency?
1.
Foods to be cautious about in G6PD deficiency: Fava bean products and mint products, such as chewing gum, Mentholatum, Green Oil, White Flower Oil, and mouthwash, may contain mint, so please be very careful.

2.
Patients with G6PD deficiency should avoid fava bean products.
The level of G6PD enzyme deficiency varies among individuals, and children are generally more sensitive compared to adults, making it relatively more dangerous.
It is essential to carry an alert card when seeking medical attention, and it is best if your National Health Insurance IC card indicates any drug allergies.
This way, wherever you go, your health records are noted.
Additionally, avoid aspirin and sulfa drugs.
3.
It is best to avoid using Chien-Ho mint sticks that contain menthol oil.
4.
Mentholatum AD ointment also contains camphor and menthol, so it is advisable not to use it.
If you have a wound, you can use neomycin ointment, which is an antibiotic ointment.
5.
Rosemary essential oil: Since we do not know if it contains mint, some individuals may experience hemolytic reactions while others may not.
Therefore, please be cautious.
If you experience symptoms such as anemia, pallor, rapid heartbeat, shortness of breath, decreased activity, fatigue, or tea-colored urine, it may indicate accidental ingestion or use of something that triggers symptoms, leading to acute hemolytic reactions.
Seek medical attention promptly.
6.
Is it necessary to completely avoid using scents like mint, lavender, rosemary, and sage if one has G6PD deficiency? Not necessarily.
I have a friend with G6PD deficiency who uses them without any issues, but it is crucial to be very careful and monitor for side effects.
Please use any essential oils in small amounts, and if there are no side effects, you may continue using them.
Wishing you good health.

Reply Date: 2019/08/21

More Info


Favism, or G6PD deficiency, is a genetic condition that affects the body's ability to process certain substances, particularly those found in fava beans and some other foods and medications. Individuals with this condition can experience hemolytic anemia when exposed to certain triggers, including specific medications and essential oils. Given your concerns about using various products while managing favism, let’s address each item you mentioned.

1. Menthol Stick (千鶴薄荷棒): Menthol is generally considered safe for topical use in individuals with G6PD deficiency. However, it’s important to be cautious, as some sources suggest that menthol can potentially trigger hemolysis in sensitive individuals. If you have been using it without any adverse effects, you may continue, but monitor for any signs of hemolysis, such as fatigue, jaundice, or dark urine. If you notice any symptoms, discontinue use immediately and consult your healthcare provider.

2. Mentholatum AD Cream (曼秀雷敦AD安膚康軟膏): Similar to the menthol stick, this cream is typically safe for topical application. It contains menthol, which may cause concern, but many individuals with G6PD deficiency use it without issues. If you find it effective for your skin conditions and have not experienced any adverse reactions, it may be safe to continue using it. If you need alternatives, consider using plain petroleum jelly or aloe vera gel for skin irritation, as these are generally safe and soothing.

3. Rosemary Essential Oil (迷迭香精油): Essential oils can be tricky for individuals with G6PD deficiency. Rosemary oil is not typically listed among the oils to avoid, but it’s essential to use it cautiously. If you choose to use it, ensure it is well-diluted and monitor for any adverse reactions. If you experience any symptoms of hemolysis, discontinue use immediately.

4. Johnson's Baby Lavender Lotion (嬌生嬰兒薰衣草身體乳液): Lavender is often mentioned in discussions about G6PD deficiency, but the risk associated with lavender products is generally low. Many individuals with favism use lavender-scented products without issues. However, if you notice any adverse reactions, it’s best to stop using it. As for the concern about exposure to lavender in other products, it’s wise to limit your exposure to known triggers, but occasional exposure in small amounts is unlikely to cause significant harm.

In summary, while many individuals with G6PD deficiency can use these products without issues, it is crucial to remain vigilant. Monitor your body’s responses to these products, and if you experience any symptoms of hemolysis, such as fatigue, jaundice, or dark urine, seek medical attention promptly. Additionally, it’s advisable to consult with a healthcare provider familiar with G6PD deficiency for personalized recommendations, especially considering your history of anemia and other health concerns. They can provide tailored advice and possibly suggest safer alternatives for your skincare and symptom management.

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