Dry Eye and Its Impact on Myopia Progression - Ophthalmology

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Myopia issues


Hello Doctor, I am 20 years old and have been experiencing dry eye issues for the past month.
Initially, it was a mild discomfort, but after using artificial tears for a month, the symptoms have worsened.
I visited the hospital four times yesterday, and my dry eye index was measured at 2 and 7.
Is this considered serious?
Additionally, I am confused because my vision was measured at nearly 400 less than a month ago (since I switched clinics), but yesterday it was measured at 500 in both eyes, despite significantly reducing my screen time.
The sudden increase in my prescription within a month is alarming to me.
Could this be temporarily related to my dry eyes?
Previously, the doctor prescribed dilating drops, but yesterday I was given methacholine and phenylephrine, which seem completely opposite to the previous medication.
Lastly, does 0.01% Mydriacyl eye drops help in slowing down myopia? Thank you for your patient response.

Niming, 20~29 year old female. Ask Date: 2019/08/22

Dr. Gao Pilin reply Ophthalmology


Hello: A dry eye test result of 5mm or less indicates significant dry eye disease.
A result of 2mm is considered quite severe.
A change in prescription from 400 to 500 within a month is somewhat excessive; this is more likely related to accommodation issues.
If you stop using the cycloplegic agent, you may also experience this phenomenon, but it should not be attributed to dry eye.
It would be prudent to conduct further tests to confirm.
Cycloplegic agents relax the ciliary muscle, which helps delay myopia progression.
Methacholine sulfate causes ciliary muscle contraction, allowing you to exert less effort when viewing objects up close, thus alleviating fatigue.
The mechanisms and effects of these two medications differ.
Regarding the Madison Eyedrops, if you are referring to Madison Eyehelp 0.01%, it has a similar effect to methacholine sulfate.
If you mean Madison Atropine Eye Drops 0.01%, it is a ciliary muscle paralytic (cycloplegic agent) that helps delay myopia.
The ophthalmology department at Puzi Hospital in Taiwan is open on Monday, Tuesday, Thursday, and Friday from 8:00 AM to 12:00 PM, and Wednesday from 2:00 PM to 4:30 PM.
Online responses should only be used as a reference; it is essential to seek medical attention at a healthcare facility if necessary.
I hope to have the opportunity to serve you.
Gao Pilin

Reply Date: 2019/08/22

More Info


Hello! Thank you for reaching out with your concerns regarding dry eye and its potential impact on myopia progression. Your situation is indeed complex, and I appreciate the opportunity to provide some insights based on the information you've shared.

Firstly, it's important to understand that dry eye syndrome can significantly affect visual comfort and quality of life. The dry eye index scores you mentioned (2 and 7) suggest varying degrees of severity, with higher scores indicating more severe symptoms. The fact that your symptoms have worsened despite using artificial tears is concerning and may indicate that your eyes are not adequately responding to the treatment. This could be due to several factors, including the type of artificial tears used, the underlying cause of your dry eye, or even environmental factors.

Regarding your vision changes, it's not uncommon for individuals with dry eye to experience fluctuations in visual acuity. Dryness can lead to instability in the tear film, which is essential for clear vision. When the tear film is disrupted, it can cause blurred vision, which might explain the increase in your refractive error from 400 to 500 in such a short time. However, this increase in myopia is also concerning, especially since you mentioned that you've reduced your screen time. While dry eye itself is not typically a direct cause of myopia progression, the discomfort and visual disturbances associated with dry eye can lead to increased eye strain, which may exacerbate myopia in some individuals.

The medications prescribed to you, including the new one (likely a form of anti-inflammatory or lubricating agent), may be aimed at addressing the underlying inflammation associated with your dry eye. It's not unusual for doctors to switch medications based on the patient's response and the specific symptoms presented. The use of a medication like cyclosporine (Restasis) or lifitegrast (Xiidra) can help increase tear production and reduce inflammation, which may improve your dry eye symptoms over time.

As for the eyedrops you mentioned (0.01% atropine), there is evidence suggesting that low-dose atropine can help slow the progression of myopia in children and young adults. However, the exact mechanism is not fully understood, and its effectiveness can vary from person to person. It's essential to discuss this with your eye care provider to determine if this treatment is appropriate for your specific situation.

In summary, your dry eye symptoms and the recent increase in myopia are concerning and warrant further investigation. It would be beneficial to have a comprehensive evaluation by an eye care professional who can assess the underlying causes of your dry eye and myopia progression. They may recommend additional treatments, lifestyle modifications, or even specialized contact lenses designed for dry eye patients, such as scleral lenses, which can provide a protective layer over the cornea and help maintain moisture.

In the meantime, consider implementing some general strategies to manage your dry eye symptoms, such as:
1. Frequent Use of Artificial Tears: Opt for preservative-free artificial tears, as they are less likely to irritate your eyes.

2. Environmental Modifications: Use a humidifier in dry environments, take breaks during prolonged screen time (the 20-20-20 rule: every 20 minutes, look at something 20 feet away for 20 seconds), and avoid direct airflow from fans or air conditioning.

3. Dietary Considerations: Omega-3 fatty acids may help improve tear production, so consider incorporating more fish or flaxseed into your diet.

4. Regular Follow-ups: Keep in close contact with your eye care provider to monitor your symptoms and adjust treatment as necessary.

I hope this information helps clarify your concerns and provides a pathway for managing your symptoms effectively. Please don't hesitate to reach out to your healthcare provider for personalized advice tailored to your specific needs.

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