Unexplained High Fever and Headache: Possible Neurological Concerns - Neurology

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Unexplained high fever and headache?


Hello, Doctor.
On the morning of September 6th, I experienced a sudden high fever reaching 40 degrees Celsius accompanied by severe headaches.
After taking antipyretics, my temperature dropped to 38 degrees but did not return to normal.
I did not have any cold symptoms (such as nasal congestion, cough, or sore throat) and went to the emergency room that afternoon.
Emergency tests revealed a white blood cell count of 25,000 and an inflammatory index of 30.
A CT scan showed no abnormalities, and I was prescribed antibiotics and other medications to rest at home.
Although the fever subsided, the headache persisted.

On the morning of September 9th, I had another fever reaching 38 degrees, and despite continuous use of antibiotics and pain relievers, the headache remained.
Therefore, I returned to the emergency room.
Further tests showed a white blood cell count of 22,000 and an inflammatory index of 24.
I also reported lower back pain on both September 6th and 9th, and on the 9th, I was unable to bend over.
After receiving an antibiotic injection in the emergency room on September 9th, the doctor determined I could go home since the fever had subsided.
However, today (September 10th), the headache persists, and I have started to notice purulent discharge from the urethral opening, although urination is not painful.
Current status: No fever, persistent headache, lower back pain, urethral discharge (white), slight dizziness, occasional visual disturbances, and difficulty taking deep breaths.
The emergency physician advised me to see a neurologist, but all nearby hospitals' neurology departments are fully booked and not accepting appointments.
I would like to ask the doctor what my current condition might indicate, whether the referral to neurology is appropriate, and if it is necessary to travel to a medical center in another county.

Zheng, 20~29 year old female. Ask Date: 2019/09/11

Dr. Jiang Junyi reply Neurology


Hello: I apologize for the late response to your question.
You mentioned experiencing headaches, lower back pain, white discharge from the urethra, mild dizziness, occasional visual disturbances, and difficulty taking deep breaths.
These symptoms may suggest an infection, particularly a urinary tract infection.
However, the likelihood of urinary tract infections in males is relatively low, and we must consider sexually transmitted infections as a potential diagnosis.
Since infections can be acute, if symptoms persist, it is advisable to seek emergency medical care.
You may also need to consult a neurologist for the related symptoms.
Neurology clinics primarily treat chronic conditions or mild cases, and it is not recommended to travel across counties for care.
The most crucial aspect of managing infections is the culture of the relevant pathogens.
If a referral to a medical center is necessary, it is recommended that a physician assess the required assistance before making the referral.
Wishing you good health and safety.
Best regards, Dr.
Jiang, Department of Internal Medicine, Taoyuan Hospital.

Reply Date: 2019/09/11

More Info


Your symptoms of unexplained high fever, severe headache, and additional signs such as lower back pain and unusual discharge from the urethra raise several important medical considerations. Given the complexity of your situation, it is crucial to approach this systematically.

Initially, the combination of high fever (up to 40 degrees Celsius), elevated white blood cell count (25,000), and inflammatory markers suggests a significant underlying infection or inflammatory process. The absence of typical respiratory symptoms (like cough or sore throat) makes common viral infections less likely. Instead, we should consider other potential sources of infection, such as urinary tract infections (UTIs), which can sometimes present with systemic symptoms like fever and headache.

The fact that you experienced a recurrence of fever and persistent headache, despite antibiotic treatment, indicates that the infection may not be fully resolved or that there could be another underlying issue. The presence of white discharge from the urethra could suggest a urinary tract infection or possibly a sexually transmitted infection (STI), which may require specific testing and treatment.
Additionally, the lower back pain you mentioned could be indicative of a kidney infection (pyelonephritis), especially if it is accompanied by urinary symptoms. This condition can lead to systemic symptoms like fever and headache, and it often requires more aggressive treatment, including intravenous antibiotics, particularly if there is concern for complications.

Your ongoing headache, even after the fever has subsided, is concerning and warrants further evaluation. Headaches can be multifactorial, but in the context of your other symptoms, they could be related to the infection, dehydration, or even a more serious condition such as meningitis, which is an inflammation of the protective membranes covering the brain and spinal cord. Given that you have experienced severe headaches, it is essential to rule out any neurological complications.

In terms of the appropriate medical specialty, seeing a neurologist is indeed a reasonable step, especially if your symptoms persist or worsen. However, given the acute nature of your symptoms and the potential for a serious underlying infection, it may be more appropriate to seek immediate care in an emergency department or an infectious disease specialist if you cannot access a neurologist promptly.
If local hospitals are unable to accommodate you, and your symptoms are severe or worsening, it may be necessary to travel to a medical center that can provide the necessary evaluations and treatments. This is particularly important if you experience new symptoms such as difficulty breathing, severe dizziness, or any neurological signs like confusion or weakness.

In summary, your symptoms suggest a possible serious infection that may require further investigation and treatment. It is crucial to follow up with healthcare professionals who can perform the necessary tests, including urine cultures, imaging studies, and possibly lumbar puncture if there is concern for meningitis. Do not hesitate to seek immediate medical attention if your condition deteriorates or if you have any new concerning symptoms. Your health and safety are paramount.

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