Gastrointestinal issues
Hello Doctor, three years ago I underwent a colonoscopy due to blood in my stool, which revealed diverticula and hemorrhoids.
Recently, I have occasionally experienced diarrhea with blood streaks (approximately five times in the past two years).
I have returned for follow-up visits, and the doctor performed occult blood tests (Occult blood (EIA/LIA)) and pus cell tests (Pus cell (WBC)), both of which returned normal results.
However, today I experienced diarrhea again with blood streaks.
What should I do? The occult blood result was negative, and the pus cell result was absent.
Why am I seeing blood with the naked eye when the test results are normal? I would like to know if ulcerative colitis or Crohn's disease can be detected through occult blood tests (Occult blood (EIA/LIA)) and pus cell tests (Pus cell (WBC)).
I have had many consultations and tests already, and I am unsure if it is necessary to undergo another colonoscopy (which I am not keen on).
However, the symptoms make me feel anxious and helpless.
I would appreciate your guidance.
Thank you.
W, 20~29 year old female. Ask Date: 2019/09/22
Dr. Ke Fangxu reply Surgery
There are many reasons for a negative fecal occult blood test, including the possibility that there was no bleeding at the time of sampling or that the sampling site did not contain blood.
The most common diagnoses, such as ulcerative colitis or Crohn's disease, require colonoscopy, and pathological biopsy is also necessary; diagnosis cannot rely solely on symptoms or stool tests.
Generally, if a colonoscopy was performed three years ago, it may not be necessary to repeat it.
However, if there are concerns, you can request your physician to arrange for another examination.
Reply Date: 2019/09/22
More Info
When dealing with gastrointestinal issues, particularly the presence of blood in the stool, it is essential to understand the various diagnostic tests available and their implications. Your situation, characterized by intermittent blood-streaked diarrhea and previous diagnoses of diverticulosis and hemorrhoids, raises valid concerns about the underlying causes of your symptoms.
Firstly, it is important to note that the presence of blood in the stool can arise from various sources within the gastrointestinal tract. Common causes include hemorrhoids, diverticular disease, inflammatory bowel diseases (IBD) such as ulcerative colitis and Crohn's disease, gastrointestinal infections, and even malignancies. Given your history of diverticulosis and hemorrhoids, these could certainly be contributing factors to your symptoms.
The tests you mentioned—occult blood testing and pus cell examination—are useful but have limitations. The occult blood test is designed to detect hidden blood in the stool that is not visible to the naked eye. However, it is important to understand that this test can yield false negatives, especially if the bleeding is intermittent or if the blood is not present in the sample tested. Factors such as the timing of the test, the presence of vitamin C, and the method of stool collection can all influence the results.
In your case, the negative results for both the occult blood and pus cells suggest that there is no significant ongoing inflammation or bleeding detectable at the time of testing. However, the intermittent nature of your symptoms—seeing blood only occasionally—could mean that the bleeding is not consistent enough to be captured in the tests performed.
Regarding your concerns about ulcerative colitis or Crohn's disease, these conditions can sometimes present with symptoms that are not always detectable through routine stool tests. While occult blood tests can indicate gastrointestinal bleeding, they do not specifically diagnose IBD. Inflammatory bowel diseases often require more comprehensive evaluation, including colonoscopy, to visualize the intestinal lining and obtain biopsies for histological examination.
Given your apprehension about undergoing another colonoscopy, it is understandable. However, if your symptoms persist or worsen, it may be necessary to reconsider this option. A colonoscopy remains the gold standard for diagnosing conditions like ulcerative colitis and Crohn's disease, as it allows for direct visualization and assessment of the colon and rectum.
In the meantime, it may be beneficial to keep a detailed diary of your symptoms, including the frequency and characteristics of your bowel movements, any associated pain, dietary habits, and any potential triggers you notice. This information can be invaluable for your healthcare provider in determining the next steps in your evaluation and management.
Additionally, consider discussing with your doctor the possibility of other non-invasive imaging studies, such as a CT scan or MRI of the abdomen, which can provide further insights into your gastrointestinal health without the need for invasive procedures.
In summary, while the negative results from your recent tests are reassuring, they do not completely rule out the possibility of underlying gastrointestinal conditions. Continuous monitoring of your symptoms, open communication with your healthcare provider, and a willingness to explore further diagnostic options will be crucial in managing your health effectively. If your symptoms persist or escalate, do not hesitate to seek further evaluation, as early diagnosis and intervention can significantly improve outcomes in gastrointestinal disorders.
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