Post-Application Effects of Phenylephrine on Skin Conditions - Dermatology

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After using phenylephrine?


Hello doctor, I have been diagnosed with genital warts at the anal area.
I have undergone several sessions of electrosurgery, and later, after applying phenol, one of the warts became hard and turned white, but it hasn't fallen off yet.
Should I continue applying it? The others seem to have scabbed over, but they bleed when they fall off.
Is this normal?

A Qiang, 30~39 year old female. Ask Date: 2019/10/14

Dr. Wu Yuxin reply Dermatology


You should consult your attending physician about this issue, as they are the most familiar with your condition.

Reply Date: 2019/10/14

More Info


Phenylephrine is a medication that is primarily used as a decongestant and vasoconstrictor. However, it can also be applied topically in certain formulations to treat skin conditions, particularly those involving swelling or inflammation. In your case, it seems you are using a phenylephrine-based product for the treatment of warts (also known as condyloma acuminata) around the anal area.

When using phenylephrine for skin conditions, particularly for warts, it is essential to understand the expected effects and potential side effects. The hard, white area you are observing could be a result of the medication's action on the wart tissue. Phenylephrine works by constricting blood vessels, which can lead to a reduction in blood flow to the area, potentially causing the wart to become necrotic (die off) and eventually fall off. This process can take time, and the appearance of the wart may change as it responds to treatment.

It is not uncommon for warts to become crusty and bleed as they begin to resolve. The formation of a scab is part of the healing process, indicating that the body is working to remove the wart tissue. However, if you notice excessive bleeding, pain, or signs of infection (such as increased redness, swelling, or pus), you should consult your healthcare provider immediately.

Regarding whether to continue applying the phenylephrine, it is crucial to follow the guidance of your healthcare provider. If the wart is showing signs of improvement (i.e., changes in color, size, or texture), continuing treatment may be beneficial. However, if you have concerns about the hardness or the white appearance of the wart, or if you experience any adverse effects, it is advisable to seek medical advice. Your healthcare provider may recommend a different treatment approach or adjust your current regimen based on your specific condition and response to the medication.

In summary, while phenylephrine can be effective in treating certain skin conditions, including warts, it is essential to monitor the area for any changes and consult with your healthcare provider for personalized advice. They can provide guidance on the appropriate duration of treatment and any additional measures you may need to take to ensure proper healing and avoid complications.

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