Safe Medication During Pregnancy: Throat Pain Relief at 26 Weeks - Pharmacology

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Is it safe to take the medication prescribed by the doctor for a sore throat at 26 weeks of pregnancy?


Hello, I am currently 26 weeks pregnant and have been experiencing a sore throat.
My doctor prescribed me 1.
Guo Jia Shi Tan (Shitan) 2.
Chang Ning (Cetia) 3.
Pu Chu Tong (Paramol).
I would like to know if these three medications will have any effects on the fetus.
Thank you!

Niming, 30~39 year old female. Ask Date: 2019/10/23

Dr. Huang Shenggang reply Pharmacology


Hello, thank you for your inquiry.
Upon checking: 1.
Guojia Shitan (Bromhexine) has a pregnancy category of A.
2.
Changning Tablets (Cetirizine) has a pregnancy category of B.
3.
Puchutong Tablets (Acetaminophen) has a pregnancy category of B.
This information is provided for your reference.
Medications in categories A and B are generally considered safe, so you can rest assured.

Reply Date: 2019/10/23

More Info


When it comes to taking medication during pregnancy, especially in the second trimester, it is crucial to consider both the safety of the medications and their potential effects on the developing fetus. At 26 weeks pregnant, you are in a stage where the fetus is more developed, but caution is still necessary when introducing any medication.

The medications you mentioned—Shitan (a cough remedy), Cetia (an antihistamine), and Paramol (a pain reliever)—need to be evaluated for their safety during pregnancy. Here’s a breakdown of each medication based on available data and general medical guidelines:
1. Shitan (Cough Remedy): This medication typically contains ingredients that may help relieve cough and phlegm. Depending on its specific formulation, it may contain substances like guaifenesin or other expectorants. Generally, expectorants are considered safe during pregnancy, but it is essential to confirm the specific ingredients and consult with your healthcare provider.

2. Cetia (Cetirizine): Cetirizine is an antihistamine commonly used for allergy relief. It is classified as Category B by the FDA, which means that animal reproduction studies have not shown a risk to the fetus, but there are no adequate studies in pregnant women. Cetirizine is often considered safe for use during pregnancy, especially for managing allergy symptoms.

3. Paramol (Paracetamol/Acetaminophen): Paracetamol is widely used for pain relief and is generally regarded as safe during pregnancy. It is classified as Category B by the FDA. The maximum recommended dose for adults is typically 4 grams per day, but it is advisable to use the lowest effective dose for the shortest duration necessary. Long-term use or high doses should be avoided unless directed by a healthcare provider.


General Considerations for Medication Use During Pregnancy:
- Consult Your Healthcare Provider: Always discuss any medications you are considering with your obstetrician or healthcare provider. They can provide personalized advice based on your medical history and the specifics of your pregnancy.

- Monitor for Side Effects: While many medications are considered safe, individual reactions can vary. Monitor for any unusual symptoms or side effects after taking a new medication.

- Hydration and Rest: In addition to medication, ensure you are staying well-hydrated and getting plenty of rest. These are essential components of recovery from any illness during pregnancy.

- Avoid Certain Medications: Some medications, particularly those that are not well-studied in pregnant populations or those that are known to have risks (like certain NSAIDs in the third trimester), should be avoided unless absolutely necessary.

In summary, the medications you have been prescribed appear to be generally safe for use during pregnancy, but it is essential to confirm their specific formulations and discuss them with your healthcare provider. They can provide the best guidance tailored to your individual health needs and the health of your baby. Always prioritize open communication with your healthcare team regarding any concerns or symptoms you experience during your pregnancy.

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