Gastrointestinal Issues: When to Consider Endoscopy - Gastroenterology and Hepatology

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Liver, gallbladder, and gastrointestinal issues?


Hello Dr.
Chen, I previously experienced gastroesophageal reflux and difficulty swallowing due to taking medication for urticaria.
While my urticaria has resolved, I am now experiencing symptoms of bloating, nausea, and upper abdominal pain, along with pain in my right shoulder, chest, and right shoulder blade.
I have consulted a gastroenterologist and have been prescribed medication, but the pain persists.
I would like to know if I need to undergo an endoscopy or if other interventions are necessary.

Sam, 20~29 year old female. Ask Date: 2019/10/23

Dr. Chen Shidian reply Gastroenterology and Hepatology


If symptoms persist, further discussion regarding endoscopy and ultrasound examination may be warranted.

Reply Date: 2019/10/23

More Info


When considering gastrointestinal issues, particularly in the context of persistent symptoms such as bloating, nausea, upper abdominal pain, and referred pain to the right shoulder and chest, it is crucial to evaluate the need for further diagnostic procedures like endoscopy.
Endoscopy, which includes procedures such as esophagogastroduodenoscopy (EGD) and colonoscopy, is often recommended when patients exhibit symptoms that suggest underlying gastrointestinal disorders that cannot be adequately diagnosed through non-invasive methods. In your case, the symptoms you described—especially the upper abdominal pain and associated discomfort—could be indicative of several conditions, including gastritis, peptic ulcers, or even esophageal issues like reflux disease.

Given your history of taking antihistamines for urticaria, which can sometimes lead to gastrointestinal side effects, it is essential to assess whether these medications may have contributed to your current symptoms. Antihistamines can cause relaxation of the lower esophageal sphincter, potentially exacerbating gastroesophageal reflux disease (GERD) and leading to symptoms like bloating and nausea.

The presence of right shoulder pain could also be significant. Referred pain from the diaphragm, which shares nerve pathways with the shoulder, can occur in cases of gallbladder disease or other upper abdominal pathologies. This makes it even more pertinent to investigate further, as gallbladder issues can manifest with similar symptoms.

In light of these considerations, here are some points to keep in mind regarding the potential need for endoscopy:
1. Persistent Symptoms: If your symptoms have not improved with medication and lifestyle changes, it may be time to consider endoscopy. This procedure allows direct visualization of the esophagus, stomach, and duodenum, helping to identify any abnormalities such as inflammation, ulcers, or lesions.

2. Severity and Duration: If your abdominal pain is severe or has been persistent, this is another indicator that further investigation is warranted. Endoscopy can help rule out serious conditions, including malignancies, especially given your family history of cancer.

3. Associated Symptoms: The combination of upper abdominal pain with nausea and referred pain to the shoulder raises the suspicion of a more complex issue that may require a comprehensive evaluation. Endoscopy can provide valuable insights into the state of your gastrointestinal tract.

4. Response to Treatment: If you have been on medication for a while without significant improvement, this could suggest that the underlying issue is not being adequately addressed. An endoscopy can help determine the cause of your symptoms and guide appropriate treatment.

5. Other Diagnostic Tests: Depending on your symptoms, your physician may also consider other diagnostic tests such as ultrasound or CT scans to evaluate the gallbladder and surrounding organs, especially if gallbladder disease is suspected.

In conclusion, while medication and lifestyle modifications are essential first steps in managing gastrointestinal symptoms, persistent or severe symptoms warrant further investigation. An endoscopy could provide critical information to guide your treatment plan and ensure that any serious conditions are identified and addressed promptly. It is advisable to discuss your symptoms and concerns with your gastroenterologist, who can help determine the best course of action based on your specific situation.

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