Short-Acting Mydriatics for Adults: Safety and Effects - Ophthalmology

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Short-acting mydriatics for adults


Due to my major, I've been staying up late staring at the computer to complete assignments.
My glasses, which I got a year ago (left eye -3.25, right eye -1.75), have recently become ineffective, so I got a new prescription (left eye -3.50, right eye -2.50).
Since I received my prescription at a clinic, I was given a short-acting mydriatic agent (tropicamide) to use before bed.
I would like to ask the doctor if using this as an adult has any preventive effect on the progression of myopia.
Will long-term use induce glaucoma? Is it necessary to apply it before bed? (I tend to stay up late, and if I apply it too late, I experience photophobia the next day.)

Mr. Zhou, 20~29 year old female. Ask Date: 2019/10/23

Dr. Gao Pilin reply Ophthalmology


Hello Mr.
Zhou: Mydriatic agents have limited effectiveness in preventing myopia in adults, and short-acting mydriatics are generally less effective for myopia prevention, so they are not necessarily required.
Additionally, long-term use does not necessarily induce glaucoma.
The ophthalmology department at Puzi Hospital in Taiwan is open on Monday, Tuesday, Thursday, and Friday mornings from 8:00 AM to 12:00 PM, and Wednesday afternoons from 2:00 PM to 4:30 PM.
Online responses should only be used as a reference; it is essential to seek medical attention at a healthcare facility when necessary.
I hope to have the opportunity to serve you.
Gao Pilin

Reply Date: 2019/10/23

More Info


When it comes to the use of short-acting mydriatics like tropicamide in adults, it is essential to understand both their safety and effects, especially in the context of your concerns regarding vision changes and potential risks such as glaucoma.

Tropicamide is commonly used in clinical settings to dilate the pupils for eye examinations. It works by blocking the action of acetylcholine on the iris sphincter muscle, leading to pupil dilation. While it is effective for diagnostic purposes, its long-term use as a treatment for refractive errors (like myopia or hyperopia) is not standard practice. The primary purpose of tropicamide is to facilitate examinations rather than to prevent or treat changes in refractive error.

Regarding your question about whether using tropicamide can prevent the progression of your refractive error, the answer is no. Tropicamide does not have any therapeutic effect on the underlying causes of myopia or hyperopia. The increase in your prescription from -3.25 to -3.50 in the left eye and from -1.75 to -2.50 in the right eye indicates a natural progression of your refractive error, which is common, especially in younger adults or those who spend extended periods focusing on near tasks, such as using computers.

As for the concern about inducing glaucoma, the risk associated with tropicamide is generally low. However, individuals with a predisposition to angle-closure glaucoma should be cautious. Tropicamide can cause a temporary increase in intraocular pressure, particularly in susceptible individuals. If you have a family history of glaucoma or have experienced symptoms like eye pain or visual disturbances, it is crucial to discuss this with your eye care provider.

Regarding the timing of administration, it is not strictly necessary to use tropicamide right before bed. The effects of tropicamide typically last for a few hours, and if you find that using it late at night leads to discomfort or light sensitivity the following day, you might consider using it earlier in the evening. However, you should follow your eye care provider's recommendations regarding the timing and frequency of use.

In summary, while tropicamide is safe for short-term use in adults for diagnostic purposes, it does not prevent the progression of refractive errors and should be used with caution in individuals at risk for glaucoma. It is essential to have regular eye examinations to monitor your vision and eye health, especially if you notice changes in your prescription. If you have further concerns about your eye health or the use of mydriatics, I recommend consulting with an ophthalmologist or optometrist who can provide personalized advice based on your specific situation.

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