Should You Get a Hepatitis B Vaccine? Your Risks - Gastroenterology and Hepatology

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Is it necessary to receive a booster dose of the hepatitis B vaccine?


Hello, Deputy Director.
My health check report shows that both Hepatitis B surface antigen (HBsAg) and Hepatitis B surface antibody (HBsAb) are negative.
Although I am not a hemodialysis patient or part of a high-risk group with multiple sexual partners, my father is a carrier of Hepatitis B.
Should I still receive the Hepatitis B vaccine? Thank you.

Chen Hao, 30~39 year old female. Ask Date: 2019/11/03

Dr. Chen Shidian reply Gastroenterology and Hepatology


It is recommended to administer an additional dose and continue monitoring, or to test for HBcAb first to determine whether to proceed with the additional dose.

Reply Date: 2019/11/03

More Info


When considering whether to get vaccinated against Hepatitis B, it’s essential to evaluate your individual risk factors and the context of your health status. Based on your health check report indicating that both the Hepatitis B surface antigen (HBsAg) and surface antibody (HBsAb) are negative, it suggests that you are not currently infected with the virus and do not have immunity against it. This situation places you at risk for potential Hepatitis B infection, especially given your family history with your father being a carrier of the virus.

Hepatitis B is primarily transmitted through blood and certain body fluids, which means that while your risk may be lower than that of individuals in high-risk groups (such as those undergoing hemodialysis or having multiple sexual partners), you are still at risk due to your familial connection. The Centers for Disease Control and Prevention (CDC) recommends vaccination for anyone who is at risk of Hepatitis B, including those who have close contact with infected individuals, such as family members.

The Hepatitis B vaccine is highly effective and is typically administered in a series of three doses. The first dose is given at a chosen time, the second dose is administered one month later, and the third dose is given six months after the first. This schedule is designed to ensure adequate immune response and long-lasting protection. Given that you have no current immunity, it is advisable to proceed with the vaccination series.
If you are concerned about the potential for exposure to the virus, it is also worth noting that Hepatitis B can survive outside the body for at least seven days, which means that contact with contaminated surfaces or materials could pose a risk, albeit a low one in everyday situations. However, the primary mode of transmission remains through direct blood-to-blood contact, unprotected sexual contact, or from mother to child during childbirth.

In terms of your father's status as a Hepatitis B carrier, it is important to maintain safe practices to minimize any risk of transmission within the household. This includes avoiding sharing personal items that may have come into contact with blood, such as razors or toothbrushes, and ensuring that any cuts or wounds are properly covered.

If you do decide to get vaccinated, it’s also a good idea to discuss with your healthcare provider any additional precautions you might take, especially considering your family history. They may recommend regular monitoring of your Hepatitis B status, especially if you have any potential exposure to the virus.

In summary, given your negative HBsAg and HBsAb results, along with your father's status as a carrier, it is prudent to get vaccinated against Hepatitis B. This vaccination will provide you with the necessary protection against the virus and help mitigate any potential risks associated with your family history. Always consult with your healthcare provider for personalized advice and to address any further concerns you may have regarding Hepatitis B and your health.

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