Gastric Polyps: Risks, Treatments, and Dietary Concerns - Gastroenterology and Hepatology

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Multiple polyps


Hello Doctor: On November 4th, I underwent an upper gastrointestinal endoscopy, and the doctor mentioned that I have over 30 polyps.
I was extremely frightened upon hearing this.
The doctor removed some for biopsy and explained that it is not possible to remove all of them during the endoscopy, stating that my procedure took three times longer than usual and that I have severe gastroesophageal reflux disease (GERD).
Additionally, I have been taking medication for GERD for a long time, which I understand are acid reducers.

1.
Do all polyps need to be biopsied, or is there a possibility of cancer in my case?
2.
Is there a connection between long-term use of GERD medication and the presence of polyps?
3.
After the procedure yesterday, I asked the doctor if I could resume my normal diet, and he said it was fine.
However, today I still feel something unusual in my stomach.
Is this situation normal?

jojo, 40~49 year old female. Ask Date: 2019/11/05

Dr. Chen Shidian reply Gastroenterology and Hepatology


Multiple gastric polyps are mostly benign, and it is sufficient to remove representative polyps for pathological examination.
Animal studies have shown that long-term use of potent acid suppressants may lead to the development of gastric polyps; whether to discontinue the medication can be discussed further with a physician.

Reply Date: 2019/11/05

More Info


Gastric polyps are growths that form on the lining of the stomach. While many gastric polyps are benign and do not pose a significant health risk, some types can be precursors to gastric cancer. The presence of multiple polyps, as in your case, necessitates careful evaluation and monitoring. Here’s a detailed response to your questions based on the information provided and general medical knowledge.

1. Are all polyps required to be biopsied? Is there a possibility of cancer?
Yes, it is generally recommended that any gastric polyp, especially those that are larger than 1 cm or those that exhibit certain characteristics (such as dysplasia), should be biopsied for histological examination. The biopsy results will help determine the nature of the polyps—whether they are hyperplastic, adenomatous, or have any signs of malignancy. The risk of cancer is higher in certain types of polyps, particularly adenomatous polyps, and in patients with a history of gastric cancer or significant dysplasia. Given that you have multiple polyps, it is prudent to follow up with your healthcare provider for the results and any necessary further action.

2. Is there a connection between long-term use of acid-reducing medications and polyps?
Long-term use of proton pump inhibitors (PPIs), which are commonly prescribed for gastroesophageal reflux disease (GERD), has been associated with the development of gastric polyps, particularly fundic gland polyps. These polyps are usually benign and do not carry a significant risk of cancer. However, the relationship between PPIs and gastric polyps is still being studied, and while PPIs can reduce stomach acid and help manage GERD symptoms, they may also alter the gastric environment in a way that promotes polyp formation. It is essential to discuss the risks and benefits of continued PPI use with your physician, especially in light of your recent findings.

3. Is it normal to feel discomfort after the procedure, and can I return to my normal diet?
After undergoing an endoscopy, it is not uncommon to experience some gastrointestinal discomfort, including bloating, gas, or mild stomach pain. This can be due to the air introduced during the procedure or the manipulation of the stomach lining. Your doctor’s advice to return to a normal diet is generally appropriate, but it is wise to start with bland, easy-to-digest foods and gradually reintroduce your regular diet. If you continue to feel discomfort or if your symptoms worsen, it is advisable to contact your healthcare provider for further evaluation.


Additional Considerations:
- Dietary Adjustments: While you can generally return to your normal diet, it may be beneficial to avoid spicy, fatty, or highly acidic foods, especially if you have a history of GERD. Incorporating a diet rich in fruits, vegetables, whole grains, and lean proteins can support overall digestive health. Staying hydrated and eating smaller, more frequent meals can also help manage symptoms.


- Follow-Up Care: Given the presence of multiple polyps and your history of GERD, regular follow-up with your gastroenterologist is crucial. They may recommend periodic surveillance endoscopies to monitor the polyps and assess any changes in your gastric health.

- Lifestyle Modifications: In addition to dietary changes, consider lifestyle modifications such as maintaining a healthy weight, avoiding tobacco, and limiting alcohol consumption, as these factors can influence gastric health and the risk of developing complications.

In summary, while the presence of gastric polyps can be concerning, many are benign. It is essential to follow up on biopsy results and maintain open communication with your healthcare provider regarding your treatment plan and any dietary or lifestyle changes that may benefit your condition.

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