Contraceptive Effectiveness After Missed Pills - Obstetrics and Gynecology

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Missed pre-exposure prophylaxis (PrEP) before sexual intercourse?


Hello doctor, I started taking the first pill of my third pack on November 15.
I forgot to take a pill on November 16, but I took one on November 17 at the usual time, making a total of two pills that day.
I had unprotected intercourse on November 21.
Is there still contraceptive effectiveness, or do I need to take emergency contraception?

Karen, 20~29 year old female. Ask Date: 2019/11/22

Dr. Huang Jianzhong reply Obstetrics and Gynecology


You started taking the first pill of the third pack on November 15.
You forgot to take a pill on November 16 but took one on November 17 at your regular time, resulting in a total of two pills taken that day.
You had unprotected intercourse on November 21.
Is there still contraceptive effectiveness, or do you need to take emergency contraception? Answer: There is still contraceptive effectiveness, and you do not need to take emergency contraception.

Reply Date: 2019/11/22

More Info


When it comes to understanding contraceptive effectiveness after missed pills, it's essential to consider how oral contraceptives work and the implications of missed doses. You mentioned that you started your third pack of birth control pills on November 15 and missed a dose on November 16, but took two pills on November 17 to catch up. Then, you had unprotected intercourse on November 21.
First, let's clarify how combination oral contraceptives (like the one you are taking) function. These pills typically contain two hormones, estrogen and progestin, which work together to prevent ovulation, thicken cervical mucus, and thin the uterine lining. For these pills to be effective, they need to be taken consistently at the same time every day.

According to the guidelines for most combination oral contraceptives, if you miss one pill, you should take it as soon as you remember, even if it means taking two pills in one day. Since you did this by taking two pills on November 17, you have effectively mitigated the risk of reduced contraceptive effectiveness from the missed pill.
However, the timing of unprotected intercourse is crucial. The effectiveness of the pill can be influenced by when you miss a dose in relation to your ovulation cycle. If you missed a pill during the first week of your pack and had unprotected sex in the same week, there is a potential risk of pregnancy, as ovulation could occur if the hormonal levels drop significantly. Since you missed a pill on November 16 and had unprotected sex on November 21, it is important to consider that the effectiveness of the pill may have been compromised, particularly if you did not take the missed pill within the 24-hour window.

In general, if you miss a pill and have unprotected intercourse, it is advisable to consider emergency contraception (EC) if you are concerned about the possibility of pregnancy. Emergency contraceptive pills are most effective when taken as soon as possible after unprotected intercourse, ideally within 72 hours, but some types can be effective up to 5 days after.

To summarize, since you missed a pill and had unprotected intercourse shortly after, there is a risk of reduced contraceptive effectiveness. While taking two pills the next day helps, it does not guarantee that ovulation was prevented. If you are worried about the possibility of pregnancy, it would be prudent to consult with a healthcare provider about the option of emergency contraception. Additionally, moving forward, consider using a backup method of contraception, such as condoms, especially during the first week of a new pack or if you miss any pills, to ensure maximum protection against unintended pregnancy.
Lastly, if you experience any unusual symptoms or have concerns about your contraceptive method, it is always best to consult with your healthcare provider for personalized advice and guidance.

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