PVCs: When to Adjust Medication and Seek Further Treatment - Cardiology

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Ventricular premature contraction (VPC)


Hello Doctor, a year ago I went to the hospital for a 24-hour electrocardiogram and was diagnosed with PVCs.
The first test showed over 7000 occurrences, and after medication treatment, the second test reduced it to over 3000 occurrences.
I am currently taking Rhythmol (propafenone) three times a day.
However, my condition doesn't seem to have improved further, especially after meals when I feel palpitations more noticeably.
At its worst, my heart skips two or three beats and then pauses for a moment, lasting for 20 to 30 minutes (even when I’m not experiencing palpitations, it seems to happen often but is just less uncomfortable).
The medication doesn’t seem to provide significant relief, and sometimes I don’t take it and still don’t have episodes.
I’m wondering if my medication needs adjustment.
Additionally, how severe does the condition need to be before considering catheter ablation? If this continues, does it indicate a higher risk of developing serious heart disease in the future?

A-Lü, 20~29 year old female. Ask Date: 2019/11/27

Dr. He Dongjin reply Cardiology


Hello, reducing from over 7000 beats to over 3000 beats is still significant, and medication adjustment is possible.
Increasing the dosage of beta-blockers or considering catheter ablation is indeed an option.
Continuous arrhythmia increases the risk of developing heart disease.
Changhua Hospital cares about your well-being.

Reply Date: 2019/11/27

More Info


Understanding Premature Ventricular Contractions (PVCs) and the management of this condition is crucial for patients experiencing symptoms like palpitations or irregular heartbeats. PVCs are extra heartbeats that originate in the ventricles and can disrupt the regular heart rhythm. While they are often benign, their frequency and the symptoms they produce can vary significantly among individuals.

In your case, the initial diagnosis of PVCs with a count of over 7000 in a 24-hour Holter monitor study is notable. After medication, the frequency decreased to around 3000 PVCs, which indicates some response to treatment. The medication you are currently taking, which includes a beta-blocker (likely the "脈律循" you mentioned), is commonly prescribed to help manage PVCs by reducing the heart's excitability and controlling the heart rate.

However, your ongoing symptoms, particularly the increased perception of PVCs after meals and the episodes of feeling like your heart is skipping beats, warrant further evaluation. It is not uncommon for patients to experience variations in symptoms based on factors such as stress, caffeine intake, or even the timing of meals. The fact that you sometimes feel palpitations even without the presence of PVCs suggests that your heart may be reacting to various stimuli, and this can be frustrating.

Regarding medication adjustment, it is essential to communicate your concerns with your healthcare provider. If you feel that the current medication is not adequately controlling your symptoms or if you are experiencing side effects, a reassessment of your treatment plan may be necessary. Your doctor might consider adjusting the dosage, switching to a different medication, or adding another agent to better manage your symptoms.

As for the question of when to consider more invasive procedures like catheter ablation (often referred to as "電燒"), this typically depends on several factors, including:
1. Symptom Severity: If your PVCs are significantly impacting your quality of life, even if they are not causing structural heart disease, this may warrant consideration for ablation.

2. Frequency of PVCs: While 3000 PVCs per day is a reduction, if they are frequent enough to cause distress or if they are associated with other concerning symptoms (like syncope or severe chest pain), further intervention may be indicated.

3. Response to Medication: If you have tried multiple medications without satisfactory relief, this could also be a reason to explore ablation.

4. Underlying Heart Condition: If there are any underlying heart conditions that could be exacerbated by PVCs, this would also influence the decision.

Regarding your concern about the long-term implications of persistent PVCs, while most individuals with PVCs do not develop significant heart disease, there is some evidence suggesting that frequent PVCs over time could potentially lead to cardiomyopathy in certain cases. However, this is generally more of a concern in patients with underlying heart disease or other risk factors.

In summary, it is crucial to maintain open communication with your healthcare provider about your symptoms and treatment effectiveness. Regular follow-ups, possibly including repeat Holter monitoring or echocardiograms, can help assess the situation. If your symptoms persist or worsen, discussing the possibility of catheter ablation or other interventions may be appropriate. Always prioritize your comfort and quality of life in these discussions, as managing PVCs is not just about numbers but also about how you feel day-to-day.

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