Missed Period and Negative Pregnancy Test: What Could Be Happening? - Obstetrics and Gynecology

Share to:

Menstruation has not occurred, and the pregnancy test is negative?


Menstruation started in early December.
I had unprotected intercourse with my boyfriend on December 10 and January 1.
My period is now 20 days late, and I have been experiencing persistent breast discomfort and swelling for several days.
On the 15th, I took a pregnancy test but did not wait for the results.
One day while showering, due to the pain, I massaged and applied pressure to my breasts and noticed that my nipples were discharging a clear fluid.
Because I was still concerned, I took another pregnancy test on the 20th, but it was still negative, although my symptoms continue.

Liangliang, 10~19 year old female. Ask Date: 2020/01/22

Dr. Lin Manying reply Obstetrics and Gynecology


Dear Miss Liang: It is recommended that if your menstruation is delayed by more than a week, you should visit a gynecologist.
Generally, if it is just a hormonal issue and there is no pregnancy, menstruation can be induced to bring it on.
Hualien Hospital, Ministry of Health and Welfare, cares about your health.

Reply Date: 2020/01/22

More Info


When faced with a missed period and negative pregnancy tests, it can be understandably concerning and confusing. In your case, you mentioned that your last menstrual period was in early December, and you have had unprotected intercourse on two occasions. Now, you are experiencing symptoms such as breast tenderness, chest discomfort, and even nipple discharge, which can all be indicative of hormonal changes in your body.

Firstly, it is important to understand that a missed period can occur for various reasons beyond pregnancy. Stress, significant weight changes, hormonal imbalances, and underlying medical conditions such as polycystic ovary syndrome (PCOS) can all disrupt your menstrual cycle. In your case, the fact that you have had unprotected intercourse raises the possibility of pregnancy, but the negative pregnancy tests suggest that this may not be the case.

Pregnancy tests work by detecting the hormone human chorionic gonadotropin (hCG) in your urine. This hormone is produced shortly after a fertilized egg attaches to the uterine lining. If you are testing too early, it is possible that your body has not yet produced enough hCG to be detected by the test. However, since you have tested multiple times and received negative results, it is less likely that you are pregnant, especially if you are experiencing symptoms that are not typical of early pregnancy.

The breast tenderness and nipple discharge you are experiencing could be related to hormonal fluctuations. Conditions such as hormonal imbalances, fibrocystic breast changes, or even benign breast conditions can cause similar symptoms. The clear discharge from the nipples, known as galactorrhea, can occur due to elevated levels of prolactin, a hormone responsible for milk production. This can be triggered by stress, certain medications, or other hormonal issues.

Given that you have missed your period for 20 days and are experiencing these symptoms, it would be advisable to consult with a healthcare provider. They can perform a more thorough evaluation, which may include blood tests to check hormone levels, a pelvic exam, or an ultrasound to assess your reproductive health. This will help rule out any underlying conditions that may be affecting your menstrual cycle and overall health.

In summary, while the possibility of pregnancy cannot be completely ruled out, the negative tests and your symptoms suggest that other factors may be at play. It is essential to seek medical advice to address your concerns and receive appropriate care. Remember, your health and peace of mind are paramount, and a healthcare professional can provide the guidance you need.

Similar Q&A

Missed Period with Negative Pregnancy Test: What's Going On?

You had unprotected intercourse on the last day of your menstrual period, but there was no ejaculation. You also had intercourse the following day. This month, your period is late, and you purchased a pregnancy test, which only showed one line, indicating a negative result. The o...


Dr. Lü Lizheng reply Obstetrics and Gynecology
The response indicates that there is likely no pregnancy. You can wait another one to two weeks, and if your period still hasn't arrived, it is recommended to take another pregnancy test. Sincerely, Dr. Lu Li-Cheng, Taoyuan Hospital.

[Read More] Missed Period with Negative Pregnancy Test: What's Going On?


Menstrual Delay: Understanding Causes When Pregnancy Tests Are Negative

Your period is 18 days late, and a pregnancy test has come back negative. You have taken medication to induce menstruation, but it has been 7 days and you still haven't gotten your period. What could be the issue?


Dr. Peng Yiguo reply Obstetrics and Gynecology
If your period is overdue and you have not used any contraception, the first thing to consider is whether you might be pregnant. A negative pregnancy test only indicates that the hormone levels may not be high enough to detect pregnancy at this time. Therefore, unless your period...

[Read More] Menstrual Delay: Understanding Causes When Pregnancy Tests Are Negative


Missed Period: Could You Still Be Pregnant Despite Negative Tests?

Hello Dr. Jan: My menstrual cycle has always been very regular, but this month it is delayed by about 7 to 10 days. I have taken several pregnancy tests, all of which have come back negative. Excluding the factor of psychological stress, is there still a possibility that I could ...


Dr. Zhan Deqin reply Obstetrics and Gynecology
It is certainly possible. If your period doesn't arrive in a few days, you should take a pregnancy test. Currently, most pregnancy tests are quite similar, but there are many factors that can affect your menstrual cycle, and sometimes it may take a few extra days for a test ...

[Read More] Missed Period: Could You Still Be Pregnant Despite Negative Tests?


Missed Period After Negative Pregnancy Tests: What's Going On?

Hello, doctor. Recently, my menstrual cycle has been irregular. I had sexual intercourse with ejaculation inside, and my period is a week late. I have taken two urine pregnancy tests, and both results were negative. However, why hasn't my period arrived yet? Am I still pregn...


Dr. Zhang Kunmin reply Obstetrics and Gynecology
Hello, the irregularity of your menstrual cycle makes it difficult to determine whether your intercourse occurred during the ovulation period. Additionally, urine tests cannot detect pregnancy immediately after implantation. It is advisable for you to consult a physician for an e...

[Read More] Missed Period After Negative Pregnancy Tests: What's Going On?


Related FAQ

Pregnancy Test

(Obstetrics and Gynecology)

Delayed Menstruation

(Obstetrics and Gynecology)

Menstrual Abnormalities

(Obstetrics and Gynecology)

Am I Pregnant?

(Obstetrics and Gynecology)

Premenstrual Syndrome

(Obstetrics and Gynecology)

Due Date

(Obstetrics and Gynecology)

Hormonal Imbalance

(Obstetrics and Gynecology)

Pregnancy Bleeding

(Obstetrics and Gynecology)

Pregnancy Likelihood

(Obstetrics and Gynecology)

Can I Get Pregnant?

(Obstetrics and Gynecology)