Alternatives for Medical Abortion: What to Do If You Can't Swallow Pills - Obstetrics and Gynecology

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Medication abortion


If someone has difficulty swallowing pills, what should they do for a medical abortion? Can RU486 be crushed into powder? Is it still effective when crushed?

Yuan, 20~29 year old female. Ask Date: 2020/01/25

Dr. Zhang Kunmin reply Obstetrics and Gynecology


Hello, the inquirer: Currently, if medication is not an option based on the relevant experimental data, surgical intervention may be necessary.
Thank you! Wishing you peace and health, Dr.
Zhang.

Reply Date: 2020/01/25

More Info


When considering alternatives for medical abortion, particularly for individuals who cannot swallow pills, it is essential to understand the options available and the implications of modifying medication forms. Medical abortion typically involves the use of two medications: mifepristone (often referred to as RU486) and misoprostol. Mifepristone is taken first to block progesterone, a hormone necessary for pregnancy continuation, followed by misoprostol, which induces contractions to expel the pregnancy.

For those who have difficulty swallowing pills, there are a few alternatives to consider:
1. Liquid Formulations: Some medications may be available in liquid form. It is important to consult with a healthcare provider to see if mifepristone or misoprostol can be obtained in a liquid formulation. This would allow for easier administration without the need to swallow pills.

2. Crushing Pills: While it is technically possible to crush mifepristone and misoprostol, this should only be done under the guidance of a healthcare provider. Crushing pills can alter the way the medication is absorbed in the body, potentially affecting its efficacy. For mifepristone, there is limited research on the effects of crushing, and it is generally recommended to take it as prescribed. Misoprostol, on the other hand, can sometimes be administered sublingually (under the tongue) or buccally (between the gum and cheek), which may enhance absorption and effectiveness.

3. Alternative Administration Routes: Misoprostol can be administered vaginally, which is another option for those who cannot swallow pills. This method has been shown to be effective and may be preferable for some individuals.

4. Consultation with Healthcare Providers: It is crucial to have a thorough discussion with a healthcare provider about your specific situation. They can provide guidance on the best methods for administering the medications and discuss any potential risks or side effects associated with altering the form of the medication.

5. Support Services: If you are considering a medical abortion, it is also beneficial to reach out to support services or organizations that specialize in reproductive health. They can offer resources, counseling, and assistance in navigating the process.

In summary, while there are alternatives for those who cannot swallow pills, it is vital to approach this situation with caution and professional guidance. Crushing pills or altering their form can impact their effectiveness, so consulting with a healthcare provider is essential to ensure safety and efficacy. Always prioritize open communication with medical professionals to explore the best options tailored to your needs.

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