Cell Atypia and Inflammatory Pigmentation in Dermatology

Cellular atypia & inflammatory pigmentation

Hello, Doctor! I have three questions to ask you:
1.
I previously had a mole approximately 0.1 cm in size excised for examination, and the report mentioned "focal mild cellular atypia." To be cautious, should any cellular atypia warrant excision?
2.
There is another mole located 1 cm away from the excised mole that was also found to be enlarging.
The outpatient physician indicated that the insurance only covers the excision of one mole at a time.
Should this unexcised mole also be removed for safety?
3.
Over the past six months, I have noticed black spots appearing on the skin of my arm.
They feel flat and seem to be concentrated around hair follicles.
I have undergone blood tests and a biopsy, and the report indicated inflammatory hyperpigmentation.
The phenomenon of pigmentation continues to appear, and it seems that the other arm has also started to show similar spots.
What further follow-up should be done, Doctor? I appreciate your time and assistance! Thank you!

mà, 40~49 year old female. Ask Date: 2020/02/21

Dr. Wu Yuxin reply Dermatology

1.
Yes.
2.
If you are concerned, you may consider surgical removal.
3.
Without seeing the lesion, it is impossible to determine the issue.
If it is troubling you, please seek medical attention promptly.

Reply Date: 2020/02/21

More Info

Understanding cell atypia and inflammatory pigmentation in dermatology is crucial for effective diagnosis and treatment. Let’s break down your questions and concerns regarding these issues.

1. Cell Atypia and Its Implications: The term "focal mild cellular atypia" indicates that there are some abnormal cells present in the tissue sample from the mole (nevus) that was excised. While mild atypia can sometimes be benign, it can also be a precursor to more serious conditions, including melanoma. The decision to excise a mole with atypical features often depends on various factors, including the degree of atypia, the patient's history, and the characteristics of the mole itself. If there is any uncertainty or if the atypia is concerning, it is generally advisable to remove the mole to ensure that any potential malignancy is addressed. Consulting with a dermatologist who can evaluate the specifics of your case is essential.

2. Management of Adjacent Moles: Regarding the mole that is adjacent to the one that was excised, if it has similar characteristics and has also increased in size, it may warrant further evaluation. The fact that your healthcare provider mentioned that insurance typically covers the removal of one mole at a time does complicate matters. However, if there are clinical concerns about the second mole, it is important to discuss these with your dermatologist. They may recommend monitoring it closely or potentially removing it if it shows signs of change or if there is a significant concern based on your medical history.

3. Inflammatory Pigmentation: The appearance of flat black spots on your arms, particularly if they are associated with inflammation, suggests a condition known as post-inflammatory hyperpigmentation (PIH). This occurs when the skin darkens in response to inflammation, which can be caused by various factors, including acne, eczema, or other dermatological conditions. The fact that you have had blood tests and a biopsy that confirmed inflammatory pigmentation is a good step in understanding the underlying cause. Treatment options for PIH include topical agents such as hydroquinone, retinoids, or azelaic acid, which can help lighten the pigmentation over time. Additionally, sun protection is crucial, as UV exposure can exacerbate pigmentation issues.

In summary, it is essential to maintain open communication with your dermatologist regarding your concerns about cell atypia and the management of moles. Regular follow-ups and monitoring of any changes in your skin are vital. If you notice any new symptoms or changes in existing moles, do not hesitate to seek medical advice. It is also beneficial to discuss treatment options for post-inflammatory pigmentation to help manage the appearance of your skin effectively. Always prioritize your skin health and ensure that you are proactive in addressing any concerns with your healthcare provider.

Similar Q&A

Understanding Skin Patches: Possible Causes and Conditions

Hello doctor, I have developed patchy spots on my left arm that are slightly lighter in color than my normal skin, but not as white as vitiligo. There is also some hyperpigmentation around the edges. I have a history of atopic dermatitis. What could this condition be?

Dr. Wu Yuxin reply Dermatology
Without actually seeing the lesion, it is impossible to determine the issue. If it is very concerning, please seek medical attention as soon as possible. A proper examination is necessary to understand the problem and to address it appropriately.

Understanding Nevi and Post-Inflammatory Hyperpigmentation in Dermatology

Dear Dr. Wu, Thank you very much for your personal advice regarding the article "<a href='https://adoctor.tw/article/151906'>#151906 Black Dots on the Scalp</a>". I would like to seek your expertise from a dermatological education and knowledge pe...

Dr. Wu Yuxin reply Dermatology
1. Can 2. Can 3. Can 4. Cannot

Understanding Joint Pigmentation: Causes and Solutions

Hello, I have a question. I have what seems to be pigment deposits around my joints. It's present in my wrists and finger joints, and it appears to be a brownish, rough texture. What could this issue be? Thank you for your guidance.

Dr. Hong Zhengsheng reply Dermatology
Hello, gentleman: Based on your description, it is currently difficult to determine your specific condition. You mentioned in your letter that "there seems to be something like pigmentation deposits in my joints. It is present in the wrist and finger joints, resembling a bro...

Understanding Skin Hyperpigmentation: Causes and Solutions for Darkened Areas

Five years ago, I noticed darkening between my armpits and wrists, but the pigmentation in my armpits has not improved. I have been plucking hairs one by one with tweezers. I have heard that plucking too forcefully can cause irritation and lead to pigmentation, but I did not use ...

Dr. Zheng Lizhen reply Dermatology
Pigmentation in the armpits may be indicative of "acanthosis nigricans." There are many potential causes for acanthosis nigricans, including genetics, hormonal factors, obesity, diabetes, and medications. It typically occurs in skin folds and presents as a brownish-blac...