Brown Stripes on Nails: Diabetes and Medication Effects - Dermatology

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Today, brown streaks were discovered on the nails?


Hello doctor, today I noticed a light brown stripe about 1mm wide on my left middle finger.
I was diagnosed with type 2 diabetes six months ago and have been taking Metformin.
Could this be related to my condition or the medication? Also, what could the color of the stripe indicate? The black line does not extend to the skin in front of the nail.

Wang, 20~29 year old female. Ask Date: 2020/03/03

Dr. Wu Yuxin reply Dermatology


It should be fine.

Reply Date: 2020/03/03

More Info


The appearance of brown stripes on the nails can be concerning, especially for individuals with underlying health conditions such as diabetes. In your case, you mentioned that you have been diagnosed with type 2 diabetes and are taking Metformin. It is important to understand the potential causes of these brown stripes and whether they are related to your diabetes or the medication you are taking.

Firstly, brown stripes on the nails can be caused by a variety of factors. One common cause is a condition known as "melanonychia," which refers to the presence of pigmentation in the nail bed. This can occur due to various reasons, including benign conditions, trauma to the nail, or more serious conditions such as melanoma. In individuals with diabetes, changes in nail appearance can sometimes be linked to poor circulation or other complications associated with the disease. However, the specific brown stripe you described, especially if it is isolated and does not extend to the surrounding skin, may not necessarily indicate a serious issue.

Metformin, the medication you are taking, is primarily used to manage blood sugar levels in individuals with type 2 diabetes. It is generally well-tolerated, and while it can have side effects, changes in nail pigmentation are not commonly reported. However, it is essential to consider that diabetes itself can lead to various skin and nail changes due to factors such as neuropathy, vascular issues, and infections.
If the brown stripe is new, persistent, or changing in appearance, it is advisable to consult a healthcare professional, preferably a dermatologist, who can examine the nail and determine if further investigation is necessary. They may perform a physical examination and, if needed, a biopsy to rule out any serious conditions.

In addition to the nail changes, it is crucial to monitor other symptoms related to your diabetes. Regular check-ups with your healthcare provider can help manage your condition effectively and address any concerns you may have regarding your health.
In summary, while the brown stripe on your nail may not be directly related to your diabetes or Metformin, it is essential to have it evaluated by a medical professional to rule out any underlying issues. Maintaining good diabetes management, including regular monitoring of blood sugar levels and routine medical check-ups, will help you stay on top of your health and address any potential complications early on.

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