Steroid-Induced Eye Pressure Increase: Risks and Recovery Time - Ophthalmology

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Steroids can cause an increase in intraocular pressure?


Hello: A high school student developed increased intraocular pressure due to the use of steroid eye drops for conjunctival keratitis.
The medication has now been discontinued, and they are using 0.5% pressure-lowering eye drops.
The measured intraocular pressure is 21 mmHg.
What is the likelihood of developing glaucoma in this case? How long does it typically take for the intraocular pressure to return to normal after stopping steroids? I'm quite worried.

Chen Mama, 40~49 year old female. Ask Date: 2020/03/23

Dr. Gao Pilin reply Ophthalmology


Hello, Mrs.
Chen: Elevated intraocular pressure caused by steroids can return to normal if detected early and the medication is discontinued promptly.
It rarely causes permanent damage, so please do not worry too much.
However, it is still important to regularly monitor your intraocular pressure until it normalizes.
The ophthalmology department at Puzi Hospital in Taiwan is open on Monday, Tuesday, Thursday, and Friday from 8:00 AM to 12:00 PM, and on Wednesday from 2:00 PM to 4:30 PM.
Online responses should only be used as a reference; if necessary, you should seek medical attention at a healthcare facility.
I hope to have the opportunity to serve you.
Gao Pi-Lin

Reply Date: 2020/03/23

More Info


Steroid-induced eye pressure increase is a significant concern, especially in young patients like high school students who may be using steroid eye drops for conditions such as conjunctivitis or keratitis. The use of topical steroids can lead to elevated intraocular pressure (IOP), which is a risk factor for the development of glaucoma, a condition that can lead to vision loss if not managed properly.

When steroids are used, they can affect the drainage of aqueous humor, the fluid within the eye, leading to increased pressure. In your case, an IOP of 21 mmHg is considered elevated, as normal IOP typically ranges from 10 to 21 mmHg. The risk of developing glaucoma due to steroid use is generally associated with prolonged use and higher doses. However, if the steroid drops were used for a short period and the pressure increase is detected early, the risk of developing glaucoma is significantly reduced.

Regarding the recovery time after discontinuing steroid use, it can vary from person to person. In many cases, if the steroids are stopped promptly and appropriate measures are taken (such as using IOP-lowering medications like the 0.5% eye drops you mentioned), the IOP can return to normal levels within a few days to weeks. Continuous monitoring of the IOP is crucial during this period to ensure that it is trending downwards and returning to a safe range.

It is important to note that while the risk of permanent damage from steroid-induced IOP elevation is low, it is not zero. Regular follow-ups with an ophthalmologist are essential to monitor the IOP and assess the health of the optic nerve, which can be affected by prolonged elevated pressure. If the IOP remains elevated despite treatment, further intervention may be necessary.

In summary, while there is a risk of developing glaucoma with steroid-induced eye pressure increases, the likelihood is lower if the steroids are used for a short duration and the pressure is monitored closely. Recovery of IOP to normal levels can typically occur within a few weeks after stopping the steroids, especially with the use of IOP-lowering medications. It is advisable to maintain regular check-ups with your eye care provider to ensure that your child's eye health is closely monitored and managed effectively.

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