Addressing Concerns About Duodenal Ulcers and Medication Management - Gastroenterology and Hepatology

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Previous inquiry response concerns?


Hello Dr.
Tsai, thank you very much for your previous response.
I have some questions regarding your last answer (my current condition includes a duodenal ulcer and mild gastritis, and I have been taking three medications: Sucralfate, Magnesium Hydroxide, and Gaskin for a month):
1.
If I stop taking the medications to see if the side effects persist, will stopping the medications worsen my gastric ulcer or lead to a relapse? How long can I safely stop the medications?

2.
One medication suppresses gastric acid secretion while the other neutralizes gastric acid, which have different mechanisms of action.
Does taking these two medications together enhance their effectiveness?
3.
It is stated that clinical necessity may dictate that improvement does not require continuous medication.
Does this mean that even if I am not completely healed and experience occasional relapses for a day or two, I can refrain from ongoing medication?
4.
Generally, gastrointestinal medications have few side effects, and short-term use is not problematic.
Does this imply that taking Sucralfate, Magnesium Hydroxide, and Gaskin for six months is acceptable?
5.
A sensation of a foreign body in the throat is also a symptom of gastroesophageal reflux disease (GERD).
If there are concerns, I can consult an ENT specialist.
If medication for GERD is ineffective, should I focus on improving my lifestyle and dietary habits? I sometimes experience this sensation and sometimes I do not.
I apologize for asking so many questions, and I truly appreciate your responses.
Thank you very much!

A Ying, 40~49 year old female. Ask Date: 2020/04/02

Dr. Cai Anshun reply Gastroenterology and Hepatology


Hello: 1.
If you stop taking the medication for about 3-5 days, you can determine whether the symptoms are side effects.
If it is indeed caused by the medication, you should seek medical attention promptly to change the medication.
2.
There are two mechanisms for reducing gastric acid secretion: one is to neutralize gastric acid, which serves a different purpose.
Mild symptoms do not require this approach; it is typically used when symptoms cannot be controlled by medication.
Usually, health insurance only covers one type of medication.
3.
Yes, adjusting your diet is sufficient.
4.
Once you feel better, you can reduce the dosage; long-term use is not necessary.
Changhua Hospital cares about your health.
Dr.
Tsai An-shun.

Reply Date: 2020/04/02

More Info


Dear Patient,
Thank you for your thoughtful questions regarding your current treatment for duodenal ulcers and the medications you are taking. I appreciate your proactive approach to understanding your health better. Let’s address your concerns one by one.

1. Stopping Medication and Its Effects: It is understandable to worry about stopping medication, especially when dealing with ulcers. Generally, discontinuing medications like those you mentioned (such as proton pump inhibitors or antacids) should be done cautiously and ideally under the guidance of your healthcare provider. Stopping these medications abruptly may lead to a rebound effect, where acid production increases, potentially worsening your symptoms. However, if your doctor recommends a trial off the medication to assess side effects, they will typically suggest a specific duration, often a few days to a week, depending on your individual situation. It’s crucial to monitor your symptoms during this period and report any significant changes to your doctor.

2. Combination of Medications: You are correct that one medication suppresses acid production while the other neutralizes it. Using both types of medications can indeed provide a synergistic effect, offering better symptom relief than either would alone. This combination can be particularly effective in managing symptoms associated with ulcers and gastroesophageal reflux disease (GERD). However, it’s essential to follow your doctor's recommendations regarding dosages and duration of use to avoid potential complications.

3. Medication Duration and Symptom Management: Your understanding is correct; even if you experience occasional flare-ups, it does not necessarily mean you must continue medication indefinitely. The goal of treatment is to manage symptoms effectively while minimizing medication use when possible. If you find that your symptoms are manageable without continuous medication, your doctor may agree that it’s reasonable to take breaks or adjust your treatment plan based on your current condition.

4. Long-term Use of Gastrointestinal Medications: While many gastrointestinal medications have a favorable safety profile, long-term use should always be monitored by a healthcare professional. Medications like proton pump inhibitors (e.g., the one you referred to as "瘍寧") can have side effects if used for extended periods, such as nutrient malabsorption or increased risk of certain infections. Therefore, while taking these medications for six months may be acceptable for some patients, it’s crucial to have regular follow-ups with your doctor to assess the necessity of ongoing treatment and to evaluate any potential side effects.

5. Throat Sensation and Lifestyle Modifications: The sensation of a foreign body in the throat can indeed be related to acid reflux. If your current medication regimen is not alleviating these symptoms, it may be beneficial to explore lifestyle and dietary changes. This can include avoiding trigger foods, eating smaller meals, and not lying down immediately after eating. If symptoms persist, consulting with an ear, nose, and throat specialist may provide additional insights and management strategies.

In conclusion, it is vital to maintain open communication with your healthcare provider regarding your treatment plan. They can provide personalized advice based on your specific health needs and help you navigate any concerns about medication management and symptom control. Thank you for your questions, and I wish you the best in your recovery journey.

Warm regards,
Doctor Q&A Teams


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