Paget's Disease of the Nipple: Symptoms and Treatment Options - Breast and Thyroid

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Parkinson's disease


Doctor, I apologize for taking up your time to answer my question.
It has been a while since I've experienced itching in the area of my areola, along with peeling skin.
The peeling areas appear darker than the non-peeling areas and feel rough to the touch.
There was also a period when I had a light yellow discharge that resembled serous fluid, but I'm not sure if it was coming from the areola or the nipple.
Could this be Paget's disease? Should I see a dermatologist or a breast surgeon?

18, 10~19 year old female. Ask Date: 2020/04/21

Dr. Yuan Tianmin reply Breast and Thyroid


Generally, lesions on the nipple or areola that are irregular or have varying characteristics raise suspicion for Paget's disease.
Based on your description, it doesn't seem to fit that profile, so it would be best to have a check-up at a breast clinic.

Reply Date: 2020/04/21

More Info


Paget's disease of the nipple is a rare form of breast cancer that typically presents with specific symptoms affecting the nipple and areola. It is often associated with underlying ductal carcinoma in situ or invasive breast cancer. The symptoms you describe, including itching, peeling of the skin around the nipple, darkening of the affected area, and discharge, can indeed be indicative of Paget's disease, but they can also be related to other conditions such as eczema, dermatitis, or even infections.


Symptoms of Paget's Disease of the Nipple:
1. Itching and Irritation: Persistent itching around the nipple area is common.

2. Skin Changes: This includes redness, flaking, or peeling of the skin on the nipple and areola. The skin may appear crusty or scaly.

3. Discoloration: The affected skin may become darker than the surrounding skin.

4. Nipple Discharge: There may be a discharge from the nipple, which can be clear, yellowish, or even bloody.

5. Nipple Retraction: In some cases, the nipple may retract or become inverted.


Diagnosis:
To determine whether you have Paget's disease or another condition, a thorough evaluation is necessary. This typically involves:
- Physical Examination: A healthcare provider will examine the affected area.

- Imaging Tests: A mammogram or ultrasound may be performed to check for underlying breast abnormalities.

- Biopsy: A definitive diagnosis often requires a biopsy of the affected skin or underlying breast tissue to check for cancerous cells.


Treatment Options:
If Paget's disease is diagnosed, treatment options may include:
1. Surgery: This may involve a lumpectomy (removal of the tumor and some surrounding tissue) or mastectomy (removal of one or both breasts).

2. Radiation Therapy: This may be recommended after surgery to eliminate any remaining cancer cells.

3. Chemotherapy: In cases where the cancer has spread, chemotherapy may be necessary.

4. Hormonal Therapy: If the cancer is hormone receptor-positive, hormonal treatments may be used.


Next Steps:
Given your symptoms, it is advisable to seek medical attention promptly. You can start by visiting a dermatologist to evaluate the skin changes, but it may also be beneficial to consult a breast surgeon or an oncologist who specializes in breast diseases. They can provide a comprehensive assessment and guide you through the necessary diagnostic tests.


Conclusion:
While your symptoms could potentially indicate Paget's disease, they could also be due to other benign conditions. Early diagnosis and treatment are crucial for the best outcomes, especially if it is a cancerous condition. Therefore, do not hesitate to seek medical advice as soon as possible. Remember, it is always better to err on the side of caution when it comes to changes in your breast health.

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