Neck Masses: When to Worry About Malignancy - Oncology

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Neck mass


Hello, doctor.
I have a swollen lymph node on the right side of my neck.
I had surgery to remove it on March 23, and the results were benign.
However, after the surgery, a large lump about the size of a 10 NT dollar coin appeared in the right submandibular triangle.
It feels tight when I tilt my head back, but it is not painful and has a hard texture.
I have taken antibiotics for three weeks, and it has decreased in size but has not disappeared; it is currently about the size of a 5 NT dollar coin.

My question is: since it has been a month without disappearing and has not decreased in size, is it possible that this lump could be a malignant tumor?

Gaga, 40~49 year old female. Ask Date: 2020/04/23

Dr. Chen Sirong reply Oncology


Gaga, 41 years old, female.
Question for the doctor: Since this lump has not disappeared or decreased in size for over a month, could it possibly be a malignant tumor?
Answer: It cannot be completely ruled out.
I recommend: 1.
Follow up with your original treating physician for further observation.
2.
Consider undergoing a PET scan at your own expense, and proceed based on the results.
3.
Surgical removal and biopsy for further evaluation.

Wishing you health and happiness,
Department of Radiation Oncology, Taoyuan General Hospital, Dr.
Chen Sih-Jung.

Reply Date: 2020/04/23

More Info


When it comes to neck masses, particularly lymph nodes, it is essential to understand the various factors that can indicate whether a mass is benign or malignant. In your case, you have already undergone surgery to remove a lymph node, which was found to be benign. However, the presence of a new mass in the right submandibular area that has not resolved after three weeks of antibiotic treatment raises some concerns.

First, it is important to note that lymph nodes can become enlarged for various reasons, including infections, inflammatory conditions, and malignancies. The fact that your initial lymph node was benign is reassuring, but it does not completely rule out the possibility of malignancy in new or persistent masses. The characteristics of the mass, such as its size, consistency, and whether it is painful or fixed to surrounding tissues, can provide additional clues.

In your case, the new mass is approximately the size of a five-yen coin and has a hard consistency. While a hard mass can sometimes be associated with malignancy, it is not definitive on its own. The fact that it has decreased in size after antibiotic treatment suggests that it may be related to an inflammatory process, such as a residual infection or a reactive lymphadenopathy. However, the persistence of the mass after three weeks of antibiotics is concerning and warrants further evaluation.

The general rule of thumb in the evaluation of neck masses is the "3-3-3 rule": if a lymph node is larger than 1 cm, persists for more than three weeks, and is associated with systemic symptoms (such as weight loss, fever, or night sweats), further investigation is warranted. In your case, while the mass is not larger than 1 cm, its persistence and the fact that it is hard and non-tender suggest that it should be monitored closely.

Given your history of a previously benign lymph node and the recent development of this new mass, it would be prudent to follow up with your healthcare provider for further evaluation. This may include imaging studies, such as an ultrasound or CT scan, to assess the characteristics of the mass and its relationship to surrounding structures. If there is still concern for malignancy, a repeat fine needle aspiration (FNA) biopsy may be indicated to obtain a definitive diagnosis.

In summary, while the characteristics of the new mass are concerning, they do not definitively indicate malignancy. However, due to its persistence and your previous history, it is essential to have it evaluated further. Regular follow-up with your healthcare provider is crucial to ensure that any changes in the mass are monitored and addressed appropriately. If you experience any new symptoms, such as difficulty swallowing, changes in voice, or significant pain, you should seek medical attention promptly.

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