Side Effects of Medications: Addressing Abdominal Pain and Diarrhea - Pharmacology

Share to:

Side effects of medication?


Hello, doctor.
I have a foot fracture, and the doctor prescribed me Lysozyme chloride 30 mg/tab, Diclofenac Potassium 25 mg/tab, and Acetaminophen 500 mg/tab.
I previously had mild constipation, but after taking the medication, I often experience cramping in my lower abdomen, which leads to diarrhea.
Is this related to the medication? I have tried to stop taking the medication at noon and in the evening, and on the day I only took it in the morning, but I still experienced abdominal pain and slight diarrhea in the evening.
Should I consider changing my medication?

AA, 20~29 year old female. Ask Date: 2020/04/24

Dr. Huang Shenggang reply Pharmacology


Hello Ms.
AA: Thank you for your inquiry.
Upon review, the potential side effects of the medication may occasionally include gastrointestinal symptoms such as loss of appetite, nausea, and diarrhea.
If you experience significant discomfort, it is advisable to discontinue use and consult your physician, who can assess whether a different medication should be prescribed.
Thank you.

Reply Date: 2020/04/24

More Info


When it comes to the medications you mentioned—Lysozyme chloride, Diclofenac Potassium, and Acetaminophen—it's essential to understand their potential side effects and interactions, especially in the context of your abdominal pain and diarrhea.

1. Overview of Medications:
- Lysozyme Chloride is an enzyme that has anti-inflammatory properties and is often used to help reduce swelling and pain. It is generally well-tolerated, but gastrointestinal side effects can occur in some individuals.

- Diclofenac Potassium is a nonsteroidal anti-inflammatory drug (NSAID) that is effective for pain relief and inflammation. Common side effects include gastrointestinal discomfort, ulcers, and bleeding, particularly with long-term use or in individuals with pre-existing gastrointestinal issues.

- Acetaminophen is an analgesic and antipyretic medication. While it is generally easier on the stomach compared to NSAIDs, excessive use can lead to liver damage.

2. Abdominal Pain and Diarrhea:
- The abdominal pain and diarrhea you are experiencing could be attributed to several factors. NSAIDs like Diclofenac can irritate the gastrointestinal tract, leading to symptoms such as abdominal cramps and diarrhea. This is especially true if you have a history of gastrointestinal issues or if you are taking other medications that may exacerbate these effects.

- It is also possible that the combination of medications is contributing to your symptoms. For instance, if you are taking Diclofenac and experiencing gastrointestinal side effects, it might be worth considering whether the benefits of pain relief outweigh the discomfort caused by the medication.

3. Medication Interactions:
- While you mentioned that you have not taken these medications together, it is still important to be cautious. Taking multiple medications that can affect the gastrointestinal system can lead to compounded side effects. For example, if you are taking an NSAID and experiencing gastrointestinal distress, adding another medication that can cause similar effects may worsen your symptoms.

4. Recommendations:
- If you are experiencing significant abdominal pain and diarrhea, it may be wise to consult your healthcare provider about your symptoms. They can assess whether your current medication regimen is appropriate or if adjustments are necessary.

- You might consider discussing the possibility of switching from Diclofenac to a different pain management strategy, especially if the gastrointestinal side effects are intolerable. Alternatives could include other classes of pain relievers or adjunct therapies that do not irritate the stomach.

- Additionally, if you suspect that your symptoms are related to the medications, it may be beneficial to keep a symptom diary. Note when you take each medication and any corresponding symptoms. This information can be invaluable for your healthcare provider in determining the best course of action.

5. Conclusion:
In summary, while the medications you are taking can be effective for managing pain, they can also lead to gastrointestinal side effects, including abdominal pain and diarrhea. It is crucial to communicate openly with your healthcare provider about these symptoms, as they can help you navigate your treatment options and ensure that you are receiving the most appropriate care for your condition. If necessary, they may recommend alternative medications or additional interventions to alleviate your discomfort. Always prioritize your health and well-being by seeking professional guidance when experiencing adverse effects from medications.

Similar Q&A

Understanding Drug Side Effects: Managing Abdominal Pain and Constipation

On January 18, I went to the hospital's gastroenterology department after vomiting five times. The doctor diagnosed me with acute gastroenteritis and prescribed Mosapride citrate and Loperamide. I was advised to stop taking any other gastrointestinal medications. I followed ...


Dr. Chen Shidian reply Gastroenterology and Hepatology
If you are experiencing constipation, you may stop using Laxative and monitor the changes in your symptoms.

[Read More] Understanding Drug Side Effects: Managing Abdominal Pain and Constipation


Persistent Digestive Issues: Understanding and Managing Diarrhea Symptoms

Hello doctor, I have been experiencing gastrointestinal discomfort for the past week, with symptoms including stomach pain, nausea, and diarrhea. I have been having diarrhea every day, sometimes more than five times, and I feel the urge to use the restroom shortly after eating, w...


Dr. Hu Guozheng reply Gastroenterology and Hepatology
Based on your description, you have seen a doctor and taken medication, but your condition has not improved. Please return for a follow-up consultation with your original physician. Thank you.

[Read More] Persistent Digestive Issues: Understanding and Managing Diarrhea Symptoms


Over-the-Counter Medications for Digestive Discomfort: What to Know

Hello, doctor. I often experience gastrointestinal issues, such as stomach discomfort and diarrhea. I would like to ask if there are any medications approved by the Department of Health that can treat gastrointestinal discomfort available on the market. Since I frequently feel un...


Dr. Li Huixiong reply Internal Medicine
Although you did not mention or describe more about the symptoms you are experiencing, assuming your diet is still okay, I suspect you may be suffering from Irritable Bowel Syndrome (IBS). You can first consult a gastroenterologist for an initial evaluation. If there are no signi...

[Read More] Over-the-Counter Medications for Digestive Discomfort: What to Know


Dealing with Diarrhea from Antibiotics: Tips for Relief

Hello Doctor: I have been taking antibiotics (Amoxicillin capsules, 2 capsules every 8 hours) for about a week due to apical periodontitis. However, the inflammation has not healed, so I need to continue taking them. Unfortunately, I have been experiencing severe diarrhea, having...


Dr. Yuan Hongdao reply Gastroenterology and Hepatology
Hello: You can start by taking over-the-counter antidiarrheal medication. However, if you experience bloody stools, fever, or abdominal pain, you should consider the possibility of antibiotic-associated pseudomembranous colitis and seek medical evaluation. Sincerely, Dr. Yuan Hon...

[Read More] Dealing with Diarrhea from Antibiotics: Tips for Relief


Related FAQ

Medication Side Effects

(Gastroenterology and Hepatology)

Drug Side Effects

(Pharmacology)

Drug Side Effects

(Obstetrics and Gynecology)

Drug Side Effects

(Family Medicine)

Medication Side Effects

(Urology)

Diarrhea

(Family Medicine)

Gastrointestinal Discomfort

(Internal Medicine)

Abdominal Bloating And Pain

(Internal Medicine)

Medication Treatment

(Pharmacology)

Side Effects Of Medication

(Psychiatry)