Is My Low MCV a Sign of Iron Deficiency Anemia? - Cardiology

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Could you please tell me if this is considered iron deficiency anemia?


Hello Doctor, I received my health examination report today.
The overall assessment from the physician is normal, and there are no red flags in the test items.
However, my MCV is outside the reference range.
The company I applied to has strict reviews regarding anemia, so I would like to ask if this indicates anemia or if it is still within a normal range.
I had a stomach ulcer last year but have since recovered.
My lab results are as follows: White Blood Cell (WBC) 6.13, Red Blood Cell (RBC) 5.40, Hemoglobin (Hgb) 15.3, Hematocrit (Hct) 43.1, Mean Corpuscular Volume (MCV) 79.8 (reference range 80-94), Mean Corpuscular Hemoglobin (MCH) 28.3, Mean Corpuscular Hemoglobin Concentration (MCHC) 35.5, Platelets 284.
(P.S.
Neither of my parents has anemia.) Thank you.

Nìmíng, 20~29 year old female. Ask Date: 2020/04/27

Dr. He Dongjin reply Cardiology


Hello, you do not have anemia, so there is no need to worry.
Changhua Hospital cares about you.

Reply Date: 2020/04/27

More Info


When evaluating your blood test results, particularly the Mean Corpuscular Volume (MCV), it's important to understand what these values indicate about your health. MCV measures the average size of your red blood cells (RBCs), and a low MCV can suggest microcytic anemia, which is often associated with iron deficiency anemia or thalassemia (also known as Mediterranean anemia).

In your case, your MCV is 79.8, which is slightly below the normal reference range of 80-94. However, your hemoglobin (Hgb) level is 15.3, which is within the normal range, and your red blood cell count (RBC) is also normal at 5.40. These values suggest that while your MCV is low, you do not currently meet the criteria for anemia, as anemia is typically defined by low hemoglobin levels.

It's also worth noting that MCV can be influenced by various factors, including age, diet, and underlying health conditions. For instance, individuals with a history of gastrointestinal issues, such as your previous gastric ulcer, may experience fluctuations in iron absorption, which can affect MCV. However, since you mentioned that you have recovered from the ulcer, it is less likely to be a current contributing factor.

Regarding your concerns about iron deficiency anemia versus thalassemia, it is essential to consider your family history. Thalassemia is a genetic condition, and since you mentioned that neither of your parents has a history of anemia, the likelihood of you having inherited thalassemia is lower. Thalassemia typically presents with significantly lower MCV values (often in the range of 60-70) and may also show other abnormalities in the complete blood count (CBC).

To further investigate the cause of your low MCV, additional tests may be warranted. These could include serum ferritin, serum iron, total iron-binding capacity (TIBC), and transferrin saturation tests, which can help determine your iron status. If these tests indicate low iron stores, then iron deficiency anemia could be diagnosed. Conversely, if your iron levels are normal, it may suggest that your low MCV is not due to iron deficiency.

It's also important to consider dietary factors. A balanced diet rich in iron (found in red meat, poultry, fish, lentils, beans, and fortified cereals) can help maintain healthy iron levels. If you are concerned about your iron intake or have dietary restrictions, consulting with a nutritionist may be beneficial.

In conclusion, while your low MCV is a point of concern, it does not automatically indicate iron deficiency anemia, especially given your normal hemoglobin levels. It would be prudent to follow up with your healthcare provider for further testing to clarify the underlying cause of your low MCV and to ensure that you are not at risk for any form of anemia. Regular monitoring and a balanced diet can help maintain your overall health and address any potential deficiencies.

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